Wolf population genetics in E urope: a systematic review, meta‐analysis and suggestions for conservation and management

M Hindrikson, J Remm, M Pilot, R Godinho… - Biological …, 2017 - Wiley Online Library
The grey wolf (C anis lupus) is an iconic large carnivore that has increasingly been
recognized as an apex predator with intrinsic value and a keystone species. However …

Application of genetics and genomics to wildlife epidemiology

JA Blanchong, SJ Robinson… - The Journal of …, 2016 - Wiley Online Library
Wildlife diseases can have significant impacts on wildlife conservation and management.
Many of the pathogens that affect wildlife also have important implications for domestic …

HLA heterozygote advantage against HIV-1 is driven by quantitative and qualitative differences in HLA allele-specific peptide presentation

J Arora, F Pierini, PJ McLaren… - Molecular biology …, 2020 - academic.oup.com
Pathogen-mediated balancing selection is regarded as a key driver of host immunogenetic
diversity. A hallmark for balancing selection in humans is the heterozygote advantage at …

MHC haplotyping of SARS-CoV-2 patients: HLA subtypes are not associated with the presence and severity of COVID-19 in the Israeli population

S Ben Shachar, N Barda, S Manor, S Israeli… - Journal of Clinical …, 2021 - Springer
HLA haplotypes were found to be associated with increased risk for viral infections or
disease severity in various diseases, including SARS. Several genetic variants are …

Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation

J Rodriguez-Beltran, JCR Hernandez-Beltran… - Nature ecology & …, 2018 - nature.com
Understanding the mechanisms governing innovation is a central element of evolutionary
theory. Novel traits usually arise through mutations in existing genes, but trade-offs between …

Aeroconservation for the fragmented skies

CM Davy, AT Ford, KC Fraser - Conservation Letters, 2017 - Wiley Online Library
From birds to bacteria, airborne organisms face substantial anthropogenic impacts. The
airspace provides essential habitat for thousands of species, some of which spend most of …

Decades of population genetic research reveal the need for harmonization of molecular markers: the grey wolf Canis lupus as a case study

GA De Groot, C Nowak, T Skrbinšek… - Mammal …, 2016 - Wiley Online Library
Following protection measures implemented since the 1970s, large carnivores are currently
increasing in number and returning to areas from which they were absent for decades or …

Genetic depletion at adaptive but not neutral loci in an endangered bird species

SA Hartmann, HM Schaefer… - Molecular …, 2014 - Wiley Online Library
Many endangered species suffer from the loss of genetic diversity, but some populations
may be able to thrive even if genetically depleted. To investigate the underlying genetic …

Signals of heterogeneous selection at an MHC locus in geographically proximate ecotypes of sockeye salmon

WA Larson, JE Seeb, TH Dann, DE Schindler… - Molecular …, 2014 - Wiley Online Library
The genes of the major histocompatibility complex (MHC) are an important component of the
vertebrate immune system and can provide insights into the role of pathogen‐mediated …

Diversifying selection and climatic effects on major histocompatibility complex class II gene diversity in the greater horseshoe bat

X Li, T Liu, A Li, Y Xiao, K Sun… - Evolutionary …, 2023 - Wiley Online Library
Heterogeneous pathogenic stress can shape major histocompatibility complex (MHC)
diversity by influencing the functional plasticity of the immune response. Therefore, MHC …