The study of eukaryotic tRNA processing has given rise to an explosion of new information and insights in the last several years. We now have unprecedented knowledge of each step …
AM Pinzaru, SF Tavazoie - Nature Reviews Cancer, 2023 - nature.com
Transfer RNAs (tRNAs) have been historically viewed as non-dynamic adaptors that decode the genetic code into proteins. Recent work has uncovered dynamic regulatory roles for …
SP Hwang, H Liao, K Barondeau, X Han, C Herbert… - Cell Reports, 2025 - cell.com
Summary tRNA modifications are critical for several aspects of their functions, including decoding, folding, and stability. Using a multifaceted approach encompassing eCLIP-seq …
Y Liang, D Ji, X Ying, R Ma, W Ji - Journal of Advanced Research, 2024 - Elsevier
Abstract Background Transfer RNA (tRNA)-derived small RNA (tsRNA) represents an important and increasingly valued type of small non-coding RNA (sncRNA). The …
M Tasak, EM Phizicky - PLoS genetics, 2022 - journals.plos.org
All tRNAs have numerous modifications, lack of which often results in growth defects in the budding yeast Saccharomyces cerevisiae and neurological or other disorders in humans. In …
A Garg, AM Sanchez, M Miele, B Schwer… - Nucleic acids …, 2023 - academic.oup.com
Inorganic phosphate is an essential nutrient acquired by cells from their environment. Here, we characterize the adaptative responses of fission yeast to chronic phosphate starvation …
AM Añazco-Guenkova, B Miguel-López… - NAR …, 2024 - academic.oup.com
Recent advancements have illuminated the critical role of RNA modifications in post- transcriptional regulation, shaping the landscape of gene expression. This review explores …
MJ Yared, Y Yoluç, M Catala, C Tisné… - Nucleic Acids …, 2023 - academic.oup.com
As essential components of the protein synthesis machinery, tRNAs undergo a tightly controlled biogenesis process, which include the incorporation of numerous …
H Ohtsuka, Y Otsubo, T Shimasaki… - Molecular …, 2023 - Wiley Online Library
In the fission yeast Schizosaccharomyces pombe, the duration of survival in the stationary phase, termed the chronological lifespan (CLS), is affected by various environmental factors …