CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …

CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …

While systemic lupus erythematosus (SLE) is an autoantibody and immune complex disease
by nature, most of its organ manifestations are in fact inflammatory. SLE activity scores thus …

Objectives Composite criteria/indices are presently used to diagnose and monitor patients
with systemic lupus erythematosus (SLE). Biomarkers for these purposes would be helpful in …

Objectives To evaluate and compare the clinical efficacy of three biomarkers for interferon
(IFN) activity (measured directly and indirectly) and six traditional biomarkers in indicating …

Introduction Interstitial lung disease (ILD) is a heterogeneous group of diseases
characterized by varying degrees of lung inflammation and/or fibrosis. We investigated …

Systemic lupus erythematosus (SLE) is an incurable autoimmune disease disproportionately
affecting women. A major obstacle in finding targeted therapies for SLE is its remarkable …

Almost all humans with homozygous deficiency of C1q develop systemic lupus
erythematosus (SLE). The precise cellular mechanism (s) by which C1q prevents the …

Abstract Systemic Lupus Erythematosus (SLE) is a multisystemic autoimmune disorder
characterized by flares-ups/remissions with a complex clinical picture related to disease …

Patients with systemic lupus erythematosus (SLE) have accelerated cardiovascular disease
and dysfunctional endothelial repair mechanisms. Myeloid angiogenic cells (MACs), derived …