Metal resistance and its association with antibiotic resistance

C Pal, K Asiani, S Arya, C Rensing, DJ Stekel… - Advances in microbial …, 2017 - Elsevier
Antibiotic resistance is recognised as a major global threat to public health by the World
Health Organization. Currently, several hundred thousand deaths yearly can be attributed to …

Digital models in biotechnology: towards multi-scale integration and implementation

FSF Hartmann, IA Udugama, GM Seibold… - Biotechnology …, 2022 - Elsevier
Industrial biotechnology encompasses a large area of multi-scale and multi-disciplinary
research activities. With the recent megatrend of digitalization sweeping across all …

Population heterogeneity in microbial bioprocesses: origin, analysis, mechanisms, and future perspectives

AL Heins, D Weuster-Botz - Bioprocess and biosystems engineering, 2018 - Springer
Population heterogeneity is omnipresent in all bioprocesses even in homogenous
environments. Its origin, however, is only so well understood that potential strategies like bet …

Zinc homeostasis at the bacteria/host interface—from coordination chemistry to nutritional immunity

J Wątły, S Potocki… - Chemistry–A European …, 2016 - Wiley Online Library
Zinc is one of the most important metal nutrients for species from all kingdoms, being a key
structural or catalytic component of hundreds of enzymes, crucial for the survival of both …

Lanthanide-binding tags for 3D X-ray imaging of proteins in cells at nanoscale resolution

TW Victor, KH O'Toole, LM Easthon, M Ge… - Journal of the …, 2020 - ACS Publications
We report the application of lanthanide-binding tags (LBTs) for two-and three-dimensional X-
ray imaging of individual proteins in cells with a sub-15 nm beam. The method combines …

Endopeptidase regulation as a novel function of the Zur-dependent zinc starvation response

SG Murphy, L Alvarez, MC Adams, S Liu, JS Chappie… - MBio, 2019 - Am Soc Microbiol
The cell wall is a strong, yet flexible, meshwork of peptidoglycan (PG) that gives a bacterium
structural integrity. To accommodate a growing cell, the wall is remodeled by both PG …

Efflux-mediated tolerance to cationic biocides, a cause for concern?

ME Wand, JM Sutton - Microbiology, 2022 - microbiologyresearch.org
With an increase in the number of isolates resistant to multiple antibiotics, infection control
has become increasingly important to help combat the spread of multi-drug-resistant …

X-ray fluorescence nanotomography of single bacteria with a sub-15 nm beam

TW Victor, LM Easthon, M Ge, KH O'Toole, RJ Smith… - Scientific reports, 2018 - nature.com
X-ray Fluorescence (XRF) microscopy is a growing approach for imaging the trace element
concentration, distribution, and speciation in biological cells at the nanoscale. Moreover …

One‐carbon metabolism, folate, zinc and translation

A Danchin, A Sekowska, C You - Microbial Biotechnology, 2020 - Wiley Online Library
The translation process, central to life, is tightly connected to the one‐carbon (1‐C)
metabolism via a plethora of macromolecule modifications and specific effectors. Using …

The impact of zinc pre-exposure on ciprofloxacin resistance development in E. coli

MP Suprenant, C Ching, N Gross, I Sutradhar… - Frontiers in …, 2024 - frontiersin.org
Introduction Antimicrobial resistance (AMR) is a global health crisis that is predicted to
worsen in the coming years. While improper antibiotic usage is an established driver, less is …