Is early-onset cancer an emerging global epidemic? Current evidence and future implications

T Ugai, N Sasamoto, HY Lee, M Ando… - Nature Reviews …, 2022 - nature.com
Over the past several decades, the incidence of early-onset cancers, often defined as
cancers diagnosed in adults< 50 years of age, in the breast, colorectum, endometrium …

Colorectal cancer chemotherapy: the evolution of treatment and new approaches

R M. McQuade, V Stojanovska… - Current medicinal …, 2017 - benthamdirect.com
Colorectal cancer (CRC) is one the greatest contributors to cancer related mortality.
Although 5 year survival rate for patients at the early stage of CRC (stages I and II) is above …

American College of Gastroenterology guidelines for colorectal cancer screening 2008

DK Rex, DA Johnson, JC Anderson… - Official journal of the …, 2009 - journals.lww.com
This document is the first update of the American College of Gastroenterology (ACG)
colorectal cancer (CRC) screening recommendations since 2000. The CRC screening tests …

Smoking and colorectal cancer: a meta-analysis

E Botteri, S Iodice, V Bagnardi, S Raimondi… - Jama, 2008 - jamanetwork.com
Context Colorectal cancer is the third most common form of cancer and the fourth most
frequent cause of cancer deaths worldwide. The association between cigarette smoking and …

Lifestyle as risk factor for cancer: Evidence from human studies

N Khan, F Afaq, H Mukhtar - Cancer letters, 2010 - Elsevier
It is increasingly appreciated that the chances of developing cancer are significantly affected
by the choice of our lifestyle. There are several uncontrollable risk factors which account for …

The burden of early-onset colorectal cancer and its risk factors from 1990 to 2019: a systematic analysis for the global burden of disease study 2019

WJ Gu, JP Pei, J Lyu, N Akimoto, K Haruki, S Ogino… - Cancers, 2022 - mdpi.com
Simple Summary In this cross-sectional study, the global incidence, death, and DALY rates
of early-onset colorectal cancer (CRC) increased from 1990 to 2019, with large variations in …

Racial disparities and sex differences in early-and late-onset colorectal cancer incidence, 2001–2018

JL Petrick, LE Barber, S Warren Andersen… - Frontiers in …, 2021 - frontiersin.org
Background Colorectal cancer (CRC) incidence rates have increased in younger individuals
worldwide. We examined the most recent early-and late-onset CRC rates for the US …

Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish …

V Andersen, M Østergaard, J Christensen, K Overvad… - BMC cancer, 2009 - Springer
Abstract Background The xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1)
and Breast Cancer Resistance Protein (BCRP/ABCG2) may restrict intestinal absorption of …

Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics

DD Buchanan, K Sweet, M Drini, MA Jenkins, AK Win… - PloS one, 2010 - journals.plos.org
Background Patients with multiple serrated polyps are at an increased risk for developing
colorectal cancer (CRC). Recent reports have linked cigarette smoking with the subset of …

Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: a multicenter study

MA Anderson, E Zolotarevsky, KL Cooper… - Official journal of the …, 2012 - journals.lww.com
OBJECTIVES: The objective of this study was to examine the association between tobacco
and alcohol dose and type and the age of onset of pancreatic adenocarcinoma (PancCa) …