Biomarkers in amyotrophic lateral sclerosis: current status and future prospects

R McMackin, P Bede, C Ingre, A Malaspina… - Nature Reviews …, 2023 - nature.com
Disease heterogeneity in amyotrophic lateral sclerosis poses a substantial challenge in drug
development. Categorization based on clinical features alone can help us predict the …

In vivo mapping of sodium homeostasis disturbances in individual ALS patients: A brain 23Na MRI study

AM Grapperon, MM El Mendili, A Maarouf, JP Ranjeva… - PloS one, 2025 - journals.plos.org
Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized
by significant heterogeneity among patients. 23Na MRI maps abnormal sodium homeostasis …

Bevacizumab is associated with cerebral microstructural alterations: a DTI study in high-grade glioma

R Kassubek, D Lulé, AC Ludolph, J Kassubek… - Frontiers in …, 2023 - frontiersin.org
Background For recurrent high-grade glioma, especially glioblastoma, no standard of care
treatment exists. Due to the prolongation of progression-free survival and a cortiocosteroid …

A versatile look‐up algorithm for mapping pH values and magnesium ion content using 31P MRSI

VL Franke, J Breitling, PS Boyd, A Feignier… - NMR in …, 2024 - Wiley Online Library
31P MRSI allows for the non‐invasive mapping of pH and magnesium ion content (Mg) in
vivo, by translating the chemical shifts of inorganic phosphate and adenosine‐5 …