The existence of the neural control of mast cell functions has long been proposed. Mast cells
(MCs) are localized in association with the peripheral nervous system (PNS) and the brain …

Mast cells are innate immune cells that intersect with the adaptive immunity and play a
crucial role in the initiation of allergic reactions and the host defense against certain …

Hypertension affects 1 in 3 adults in the United States and leads to left ventricular (LV)
concentric hypertrophy, interstitial fibrosis, and increased stiffness. The treatment of cardiac …

Reduced levels of the sensory nerve neuropeptide substance P (SP) have been reported in
the diabetic rat heart, the consequence being a loss of cardioprotection in response to …

Abstract Novel Coronavirus infection (COVID-19) has become a pandemic in these days. It
is an acute respiratory and infectious disease with no known etiology and treatment. It is …

Neurokinin receptors belong to the GPCRs family and are ubiquitously expressed
throughout the nervous and immune systems. Neurokinin receptors in coordination with …

Mast cells (MCs), central players in allergy and parasitic infections, play key roles in
inflammation and fibrosis. Here, the impact of MCs on the progression of Coxsackievirus B3 …

Introduction An increasing number of studies have shed light on the role of cardiac mast
cells in the pathogenesis of hypertension-induced myocardial remodeling. Mast cells …

The foreign body response (FBR) caused by biomaterials can essentially be understood as
the interaction between the immune microenvironment and biomaterials, which has severely …

The biogenic amine, histamine, is found predominantly in mast cells, as well as specific
histaminergic neurons. Histamine exerts its many and varied actions via four G-protein …