Abstract Background Probiotic yeasts (PYs) as promising cell factories and nutraceutical
carriers have several pivotal potentials including health-promoting and bio-therapeutic …

Engineered probiotics are a kind of new microorganisms produced by modifying original
probiotics through gene editing. With the continuous development of tools and technology …

The human gastrointestinal tract is a complex and dynamic environment, playing a crucial
role in human health. Microorganisms engineered to express a therapeutic activity have …

To achieve sustainable development, alternative resources should replace conventional
resources such as fossil fuels. In marine ecosystems, many macroalgae grow faster than …

Certain probiotic microorganisms can synthesize important bioproducts, including
polysaccharides as components of cellular structure or extracellular matrix. Probiotic-derived …

Yeast has been established as a versatile platform for expressing functional molecules,
owing to its well-characterized biology and extensive genetic modification tools. Compared …

Evolutionary engineering experiments, in combination with omics technologies, revealed
genetic markers underpinning the molecular mechanisms behind acetic acid stress …

Kluyveromyces marxianus is a rapidly growing thermotolerant yeast that secretes a variety of
lytic enzymes, utilizes different sugars, and produces ethanol. The probiotic potential of this …

Background During the last decades, the advancements in synthetic biology opened the
doors for a profusion of cost-effective, fast, and ecologically friendly medical applications …

In this study, the probiotic yeast Saccharomyces boulardii was engineered to secrete the
antiviral lectin griffithsin. Twelve genetic tools with the griffithsin gene were cloned into the …