Bacterial pathogenesis in various fish diseases: recent advances and specific challenges in vaccine development

AA Irshath, AP Rajan, S Vimal, VS Prabhakaran… - Vaccines, 2023 - mdpi.com
Aquaculture is a fast-growing food sector but is plagued by a plethora of bacterial pathogens
that infect fish. The rearing of fish at high population densities in aquaculture facilities makes …

Marine Pharmacology in 2019–2021: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis and Antiviral …

AMS Mayer, VA Mayer, M Swanson-Mungerson… - Marine Drugs, 2024 - mdpi.com
The current 2019–2021 marine pharmacology literature review provides a continuation of
previous reviews covering the period 1998 to 2018. Preclinical marine pharmacology …

Antimicrobial peptide octominin-encapsulated chitosan nanoparticles enhanced antifungal and antibacterial activities

EHTT Jayathilaka, C Nikapitiya, M De Zoysa… - International Journal of …, 2022 - mdpi.com
Antimicrobial peptides (AMPs) have become a key solution for controlling multi-drug-
resistant (MDR) pathogens, and the nanoencapsulation of AMPs has been used as a …

Antimicrobial and Anti-Biofilm Peptide Octominin for Controlling Multidrug-Resistant Acinetobacter baumannii

EHTT Jayathilaka, DC Rajapaksha… - International Journal of …, 2021 - mdpi.com
Acinetobacter baumannii is a serious nosocomial pathogen with multiple drug resistance
(MDR), the control of which has become challenging due to the currently used antibiotics …

PEGylation of the antimicrobial peptide PG-1: a link between propensity for nanostructuring and capacity of the antitrypsin hydrolytic ability

W Yu, J Wang, Z Wang, L Li, W Li, J Song… - Journal of Medicinal …, 2021 - ACS Publications
The increasing prevalence of antibacterial resistance globally underscores the urgent need
for updated antimicrobial peptides (AMPs). Here, we describe a strategy for inducing the self …

Antifungal Efficacy of Antimicrobial Peptide Octominin II against Candida albicans

JNC Jayasinghe, I Whang, M De Zoysa - International Journal of …, 2023 - mdpi.com
Most clinically isolated Candida albicans strains are drug-resistant, emphasizing the urgent
need to discover alternative therapies. In this study, the previously characterized Octominin …

Transcriptome analysis revealed the synergism of novel rhodethrin inhibition on biofilm architecture, antibiotic resistance and quorum sensing in Enterococcus …

ER Tatta, S Paul, R Kumavath - Gene, 2023 - Elsevier
Enterococcus sp. emerged as an opportunistic nosocomial pathogen with the highest
antibiotic resistance and mortality rate. Biofilm is problematic primarily since it is regulated …

Biofilm formation of pathogenic bacteria isolated from aquatic animals

L De Silva, GJ Heo - Archives of Microbiology, 2023 - Springer
Bacterial biofilm formation is one of the dynamic processes, which facilitates bacteria cells to
attach to a surface and accumulate as a colony. With the help of biofilm formation …

The antibacterial activity and mechanism of a novel peptide MR-22 against multidrug-resistant Escherichia coli

C Tian, N Zhao, L Yang, F Lin, R Cai… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Bacterial infections have become serious threats to human health, and the
excessive use of antibiotics has led to the emergence of multidrug-resistant (MDR) bacteria …

In-vitro immunomodulatory responses and antiviral activities of antimicrobial peptide octominin against fish pathogenic viruses

MKHM Dias, EHTT Jayathilaka, SL Edirisinghe… - Fish & Shellfish …, 2023 - Elsevier
Antimicrobial peptides (AMPs) are considered a novel approach to stimulate fish antiviral
mechanisms for defense against a broad range of viral infections by enhancing …