Small noncoding RNAs in reproduction and infertility

Q Zhu, JA Kirby, C Chu, LT Gou - Biomedicines, 2021 - mdpi.com
Infertility has been reported as one of the most common reproductive impairments, affecting
nearly one in six couples worldwide. A large proportion of infertility cases are diagnosed as …

Perspectives in Genome-Editing Techniques for Livestock

J Popova, V Bets, E Kozhevnikova - Animals, 2023 - mdpi.com
Simple Summary Genetically modified farm animals have been actively used in a number of
applications from testing gene functions to increasing production and economic value of …

Characteristics of miRNAs present in bovine sperm and associations with differences in fertility

N Werry, SJ Russell, DJ Gillis, S Miller… - Frontiers in …, 2022 - frontiersin.org
Small non-coding RNAs have been linked to different phenotypes in bovine sperm, however
attempts to identify sperm-borne molecular biomarkers of male fertility have thus far failed to …

Bta-miR-301a targets ACVR1 to influence cleavage time and blastocyst formation rate of early embryos in cattle

H Li, J Gao, J Wang, B Zhao, X Ma… - Biology of …, 2024 - academic.oup.com
Accumulating evidence indicates that paternally derived microRNAs play a crucial role in the
development of early embryos and are regarded as the key factor in the successful …

MicroRNA-202-5p-dependent inhibition of Bcl-2 contributes to macrophage apoptosis and atherosclerotic plaque formation

F Xu, F Yao, Y Ning - Gene, 2023 - Elsevier
Background The identification of microRNA (miRNA)-related molecular mechanisms has
advanced the development of new therapeutics for atherosclerosis (AS). The roles of miR …

bta-miR-183 targets EZRIN to regulate microvilli formation and improve early development of bovine embryos

Y Wu, Z Zuo, Z Wang, H Liu, Q Zhou, S Ren… - …, 2023 - rep.bioscientifica.com
In brief Almost total lack of sperm-borne RNAs is regarded as one of the key factors that
leads to the abnormal development of somatic cell nuclear transfer embryo. This paper …

Role of miRNAs in preimplantation embryo development and their potential as embryo selection biomarkers

M Esmaeilivand, A Abedelahi, K Hamdi… - Reproduction …, 2022 - CSIRO Publishing
Context MicroRNAs (miRNAs) play different roles in oocyte fertilisation, degradation of
maternal transcripts, embryo development, and implantation. During in vitro fertilisation …

Inhibition of HSP90AA1 induces abnormalities in bovine oocyte maturation and embryonic development

B Zhao, H Li, H Zhang, X Lan, X Ren, L Zhang… - …, 2024 - rep.bioscientifica.com
In brief HSP90AA1 is a ubiquitous molecular chaperone that can resist cellular stress, such
as oxidative stress and apoptosis, and mediate the efficacy and protein folding of normal …

Bta-miR-6531 Regulates Calcium Influx in Bovine Leydig Cells and Is Associated with Sperm Motility

Q Ding, X Ding, S Xia, F Zhao, K Chen, Y Qian, S Cao… - Genes, 2022 - mdpi.com
MicroRNAs (miRNAs) play key roles in sperm as the regulatory factors involved in fertility
and subsequent early embryonic development. Bta-miR-6531 is specifically a highly …

Excluding alanine from minimum essential medium (MEM) nonessential amino acid supplementation of the culture medium facilitates post-fertilization events and …

N Itami, S Akagi, Y Hirao - Journal of Reproduction and …, 2024 - jstage.jst.go.jp
Embryonic transfer of bovine blastocysts produced by in vitro fertilization is widely utilized
despite a 9 compromised conception rate. It has been suggested that a set of four evaluation …