Disturbed flow's impact on cellular changes indicative of vascular aneurysm initiation, expansion, and rupture: A pathological and methodological review

K Sunderland, J Jiang, F Zhao - Journal of cellular physiology, 2022 - Wiley Online Library
Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …

Current mouse models of intracranial aneurysms: analysis of pharmacological agents used to Induce aneurysms and their impact on Translational Research

D Khan, X Li, T Hashimoto, R Tanikawa… - Journal of the …, 2024 - Am Heart Assoc
Intracranial aneurysms (IAs) are rare vascular lesions that are more frequently found in
women. The pathophysiology behind the formation and growth of IAs is complex. Hence, to …

Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms

Y Shima, S Sasagawa, N Ota, R Oyama… - Science translational …, 2023 - science.org
Intracranial aneurysms (IAs) are a high-risk factor for life-threatening subarachnoid
hemorrhage. Their etiology, however, remains mostly unknown at present. We conducted …

Single-cell analysis reveals the implication of vascular endothelial cell-intrinsic ANGPT2 in human intracranial aneurysm

G Yu, J Li, H Zhang, H Zi, M Liu, Q An… - Cardiovascular …, 2024 - academic.oup.com
Aims While previous single-cell RNA sequencing (scRNA-seq) studies have attempted to
dissect intracranial aneurysm (IA), the primary molecular mechanism for IA pathogenesis …

Animal models of intracranial aneurysms: history, advances, and future perspectives

H Uchikawa, R Rahmani - Translational Stroke Research, 2024 - Springer
Intracranial aneurysms (IA) are a disease process with potentially devastating outcomes,
particularly when rupture occurs leading to subarachnoid hemorrhage. While some …

Dysregulated genes and signaling pathways in the formation and rupture of intracranial aneurysm

M Kumar, K Patel, S Chinnapparaj, T Sharma… - Translational Stroke …, 2024 - Springer
Intracranial aneurysm (IA) has the potential to rupture. Despite scientific advances, we are
still not in a position to screen patients for IA and identify those at risk of rupture. It is critical …

Finite element modeling of shape memory polyurethane foams for treatment of cerebral aneurysms

HR Jarrah, A Zolfagharian, M Bodaghi - Biomechanics and Modeling in …, 2021 - Springer
In this paper, a thermo-mechanical analysis of shape memory polyurethane foams
(SMPUFs) with aiding of a finite element model (FEM) for treating cerebral aneurysms (CAs) …

Animal model contributes to the development of intracranial aneurysm: a bibliometric analysis

J Chen, J Liu, X Liu, C Zeng, Z Chen, S Li… - Frontiers in Veterinary …, 2022 - frontiersin.org
Introduction Studies on intracranial aneurysms (IAs) using animal models have evolved for
decades. This study aimed to analyze major contributors and trends in IA-related animal …

[Retracted] Effect of Cross Theoretical Model of Behaviour Change and Motivation Interview on Self‐Management Behaviour

H Wang, D Li, Y Xiong, H Huang, Q Hu… - Journal of …, 2022 - Wiley Online Library
Objective. To evaluate the effects of a trans‐theoretical model (TTM) of behavioural change
plus motivational interviewing on self‐management behavior and quality of life (QoL) in …

A systematic review of the Woven EndoBridge device—do findings in pre-clinical animal models compare to clinical results?

R Aquarius, D Elbertsen, J de Vries, HD Boogaarts… - Acta …, 2023 - Springer
Abstract Background The Woven Endobridge (WEB) is designed to treat intracranial wide-
neck bifurcation aneurysms, preventing subarachnoid hemorrhage. The translational value …