While it is universally accepted that the brain makes predictions, there is little agreement
about how this is accomplished and under which conditions. Accurate prediction requires …

The ability to recognize ordered event sequences is a fundamental component of sensory
cognition and underlies the capacity to generate temporally specific expectations of future …

Acetylcholine is a neurotransmitter that plays a variety of roles in the central nervous system.
It was previously shown that blocking muscarinic receptors with a nonselective antagonist …

The predictive coding hypothesis proposes that top-down predictions are compared with
incoming bottom-up sensory information, with prediction errors signaling the discrepancies …

Familiarity creates subjective memory of repeated innocuous experiences, reduces neural
and behavioral responsiveness to those experiences, and enhances novelty detection. The …

Parvalbumin-expressing (PV) cells are the most common class of inhibitory interneurons in
the visual cortex. They are densely connected to excitatory cells and play important roles in …

Prediction mismatch responses in cortex seem to signal the difference between an internal
model of the animal and sensory observations. Often these responses are interpreted as …

Predictive processing in the visual system is pivotal for efficient sensory-driven behaviors.
Previous research has shown that the visual system transforms sequential inputs into …

The mammalian visual system is an incredibly complex computation device, capable of
performing the various tasks of seeing: navigation, pattern and object recognition, motor …