In order to ensure normal body function, the human body is dependent on a tight control of
its blood glucose levels. This is accomplished by a highly sophisticated network of various …

Insulin is a major endocrine hormone also involved in the regulation of energy and lipid
metabolism via the activation of an intracellular signaling cascade involving the insulin …

Nonalcoholic fatty liver disease (NAFLD) is a condition in which excess fat accumulates in
the liver of a patient with no history of alcohol abuse or other causes for secondary hepatic …

▪ Abstract The discovery of the adipose-derived hormone leptin has generated enormous
interest in the interaction between peripheral signals and brain targets involved in the …

Following the discovery of leptin in 1994, the scientific and clinical communities have held
great hope that manipulation of the leptin axis may lead to the successful treatment of …

Leptin is hypothesized to function as a negative feedback signal in the regulation of energy
balance. It is produced primarily by adipose tissue and circulating concentrations correlate …

There has been great interest in dry matter intake regulation in lactating dairy cattle to
enhance performance and improve animal health and welfare. Predicting voluntary dry …

III. IGFs and Their Receptors A. IGF peptides and receptors B. Expression of IGFs and IGF
receptors in the ovary C. Role of IGFs in ovulatory function and steroidogenesis

Background—Leptin plays a role in fat metabolism and correlates with insulin resistance
and other markers of the metabolic syndrome, independent of total adiposity. Therefore, we …

Leptin, the protein encoded by the obese (ob) gene, is synthesized and released in
response to increased energy storage in adipose tissue,,,. However, it is still not known how …