Molecular and cellular mechanisms underlying anti-neuronal antibody mediated disorders of the central nervous system

MH van Coevorden-Hameete, E de Graaff… - Autoimmunity …, 2014 - Elsevier
Over the last decade multiple autoantigens located on the plasma membrane of neurons
have been identified. Neuronal surface antigens include molecules directly involved in …

[HTML][HTML] Voltage gated calcium channel antibody-related neurological diseases

CE Bekircan-Kurt, ED Çiftçi, AT Kurne… - World Journal of Clinical …, 2015 - ncbi.nlm.nih.gov
Voltage gated calcium channel (VGCC) antibodies are generally associated with Lambert-
Eaton myasthenic syndrome. However the presence of this antibody has been associated …

Antibody repertoire in paraneoplastic cerebellar degeneration and small cell lung cancer

L Sabater, R Höftberger, A Boronat, A Saiz, J Dalmau… - PLoS …, 2013 - journals.plos.org
The goal of this study is to determine whether patients with paraneoplastic cerebellar
degeneration (PCD) and small-cell lung cancer (SCLC) have a specific repertoire of …

Neuronal central nervous system syndromes probably mediated by autoantibodies

A Chefdeville, J Honnorat, CS Hampe… - European Journal of …, 2016 - Wiley Online Library
In the last few years, a rapidly growing number of autoantibodies targeting neuronal cell‐
surface antigens have been identified in patients presenting with neurological symptoms …

Lambert‐Eaton Myasthenic Syndrome; Pathogenesis, Diagnosis, and Therapy

NE Gilhus - Autoimmune Diseases, 2011 - Wiley Online Library
Lambert‐Eaton Myasthenic Syndrome (LEMS) is a rare disease with a well‐characterized
pathogenesis. In 50% of the patients, LEMS is a paraneoplastic manifestation and caused …

Favorable response to rituximab in a patient with anti‐VGCC‐positive Lambert‐Eaton myasthenic syndrome and cerebellar dysfunction

HL Pellkofer, R Voltz, T Kuempfel - Muscle & Nerve: Official …, 2009 - Wiley Online Library
Lambert‐Eaton myasthenic syndrome (LEMS) is an autoimmune disease that is
characterized by impaired transmission across the neuromuscular junction due to …

Neuro-ophthalmic manifestations of cerebellar disease

SC Beh, TC Frohman, EM Frohman - Neurologic clinics, 2014 - neurologic.theclinics.com
The cerebellum is responsible for sculpting and refining ocular movements to ensure their
precision and accuracy (to bring images to the fovea and keep them stable there), thereby …

Antibodies to neural cell surface and synaptic proteins in paraneoplastic neurologic syndromes

A Budhram, E Sechi - Handbook of Clinical Neurology, 2024 - Elsevier
Among patients with paraneoplastic neurologic syndromes (PNS), emphasis has historically
been placed on neural antibodies against intracellular proteins that have a strong …

[HTML][HTML] Non-paraneoplastic Lambert-Eaton myasthenic syndrome: a brief review of 10 cases

PJ Lorenzoni, RH Scola, CSK Kay… - Arquivos de neuro …, 2010 - SciELO Brasil
Lambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the
presynaptic neuromuscular transmission, which more frequently occurs as the remote effect …

Voltage-gated calcium channel autoimmune cerebellar degeneration: Case and study of cytotoxicity

M McKasson, SL Clardy, SA Clawson… - Neuroimmunology & …, 2016 - AAN Enterprises
Objectives: To describe response to treatment in a patient with autoantibodies against
voltage-gated calcium channels (VGCCs) who presented with autoimmune cerebellar …