Background: Light chain deposition disease (LCDD) is characterized by the tissue
deposition of monotypical immunoglobulin light chains (LCs). The aim of this study was to …

B-cell proliferative disorders may display their pathogenic effects by increased cell numbers,
increased concentrations of the molecules produced by those cells, or both …

Myeloma kidney is the major cause of severe irreversible renal failure in patients with
multiple myeloma. This tubulointerstitial injury is a direct consequence of high …

Département de Néphrologie and Unité INSERM 489, Hôpital Tenon (Assistance Publique-
Hôpitaux de Paris) and Université Pierre et Marie Curie, Paris, France alpha-1, 5%; alpha-2 …

Cast nephropathy is the most common cause of renal disease in multiple myeloma,
however, treatment with plasma exchange remains controversial even after 3 randomized …

Background: Light-chain deposition disease (LCDD) is a monoclonal gammopathy
characterized by nonamyloid deposition of light chain in various organs. A small number of …

Context.—Renal dysfunction in plasma cell dyscrasias is common. It is the second most
common cause of death in patients with myeloma. Objective.—We evaluated 77 sequential …

Renal involvement in 204 cases with multiple myeloma admitted over a 10-year period to
this tertiary care center in north India was retrospectively examined. Renal involvement …

Since the publication of High-Resolution Electrophorsesis and Immunofixation 2e, there
have been ever-increasing advances in the analyses of proteins, by electrophoresis in …

Abstract Light-, light-and heavy-, and heavy-chain deposition diseases belong to a family of
diseases that include light-chain (AL)-amyloid, nonamyloid fibrillary and immunotactoid …