SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Objectives To summarise the evidence on the duration of infectiousness of individuals in
whom SARS-CoV-2 ribonucleic acid is detected. Methods A rapid review was undertaken in …

Infectious viral load (VL) expelled as droplets and aerosols by infected individuals partly
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …

The recent emergence of B. 1.1. 529, the Omicron variant,, has raised concerns of escape
from protection by vaccines and therapeutic antibodies. A key test for potential …

The recent emergence of SARS-CoV-2 Omicron (B. 1.1. 529 lineage) variants possessing
numerous mutations has raised concerns of decreased effectiveness of current vaccines …

Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …

SARS-CoV-2 variants of concern (VOC) have arisen independently at multiple locations,
and may reduce the efficacy of current vaccines that target the spike glycoprotein of SARS …

Most human monoclonal antibodies (mAbs) neutralizing SARS-CoV-2 recognize the spike
(S) protein receptor-binding domain and block virus interactions with the cellular receptor …

SARS-CoV-2 has caused the global COVID-19 pandemic. Although passively delivered
neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism …