Functional roles of chemokine receptor CCR2 and its ligands in liver disease

S She, L Ren, P Chen, M Wang, D Chen… - Frontiers in …, 2022 - frontiersin.org
Chemokines are a family of cytokines that orchestrate the migration and positioning of
immune cells within tissues and are critical for the function of the immune system. CCR2 …

The multiple faces of CCL13 in immunity and inflammation

E Mendez-Enriquez, EA García-Zepeda - Inflammopharmacology, 2013 - Springer
Abstract CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils,
basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable …

Genetically programmable pathogen sense and destroy

S Gupta, R Weiss - US Patent App. 13/033,233, 2012 - Google Patents
0001. This application claims the benefit under 35 USC S119 (e) of US Provisional
Application Ser. No. 61/307,301, entitled “PATHOGEN SENSE AND DESTROY filed on Feb …

Characterization of the novel antibacterial peptide Leucrocin from crocodile (Crocodylus siamensis) white blood cell extracts

S Pata, N Yaraksa, S Daduang, Y Temsiripong… - Developmental & …, 2011 - Elsevier
Four novel antibacterial peptides, Leucrocin I–IV from Siamese crocodile white blood cell
extracts were purified by reverse phase high performance liquid chromatography (RP …

Antimicrobial activities of chemokines: not just a side-effect?

M Wolf, B Moser - Frontiers in immunology, 2012 - frontiersin.org
The large family of chemoattractant cytokines (chemokines) embraces multiple, in part
unrelated functions that go well beyond chemotaxis. Undoubtedly, the control of immune cell …

Structural perspectives on antimicrobial chemokines

LT Nguyen, HJ Vogel - Frontiers in immunology, 2012 - frontiersin.org
Chemokines are best known as signaling proteins in the immune system. Recently however,
a large number of human chemokines have been shown to exert direct antimicrobial activity …

Chemokine-derived peptides: novel antimicrobial and antineoplasic agents

J Valdivia-Silva, J Medina-Tamayo… - International journal of …, 2015 - mdpi.com
Chemokines are a burgeoning family of chemotactic cytokines displaying a broad array of
functions such as regulation of homeostatic leukocyte traffic and development, as well as …

[HTML][HTML] Mechanistic insights and therapeutic opportunities of antimicrobial chemokines

MA Crawford, KR Margulieux, A Singh… - Seminars in cell & …, 2019 - Elsevier
Chemokines are a family of small proteins best known for their ability to orchestrate immune
cell trafficking and recruitment to sites of infection. Their role in promoting host defense is …

Structure of chemokine-derived antimicrobial peptide interleukin-8α and interaction with detergent micelles and oriented lipid bilayers

S Bourbigot, L Fardy, AJ Waring, MR Yeaman… - Biochemistry, 2009 - ACS Publications
Interleukin-8α (IL-8α) is an antimicrobial peptide derived from the chemokine IL-8. Solution
NMR was used to determine the atomic-resolution structure of IL-8α in SDS micelles. Solid …

[HTML][HTML] Association of MCP-4, NRTN, and PD-L1 with the risk of hepatic fibrosis: A Mendelian randomization study

L Li, J Yan, Q Liu, L Ge, Y Pan, B Han, C Wang… - Medicine, 2024 - journals.lww.com
Previous studies have confirmed the affiliation between specific inflammatory cytokines and
Hepatic fibrosis (HF); however, contradictions remain in the causality. The study …