Neural oscillations are a start toward understanding brain activity rather than the end

KB Doelling, MF Assaneo - PLoS biology, 2021 - journals.plos.org
Does rhythmic neural activity merely echo the rhythmic features of the environment, or does
it reflect a fundamental computational mechanism of the brain? This debate has generated a …

The multi-partner consortium to expand dementia research in Latin America (ReDLat): driving multicentric research and implementation science

A Ibanez, JS Yokoyama, KL Possin, D Matallana… - Frontiers in …, 2021 - frontiersin.org
Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or
declining rates in North America and Europe. This scenario places unprecedented clinical …

Unifying turbulent dynamics framework distinguishes different brain states

A Escrichs, YS Perl, C Uribe, E Camara… - Communications …, 2022 - nature.com
Significant advances have been made by identifying the levels of synchrony of the
underlying dynamics of a given brain state. This research has demonstrated that non …

Whole-brain models to explore altered states of consciousness from the bottom up

R Cofré, R Herzog, PAM Mediano, J Piccinini… - Brain Sciences, 2020 - mdpi.com
The scope of human consciousness includes states departing from what most of us
experience as ordinary wakefulness. These altered states of consciousness constitute a …

Perturbations in dynamical models of whole-brain activity dissociate between the level and stability of consciousness

Y Sanz Perl, C Pallavicini, I Pérez Ipiña… - PLoS computational …, 2021 - journals.plos.org
Consciousness transiently fades away during deep sleep, more stably under anesthesia,
and sometimes permanently due to brain injury. The development of an index to quantify the …

Whole-brain modelling identifies distinct but convergent paths to unconsciousness in anaesthesia and disorders of consciousness

AI Luppi, PAM Mediano, FE Rosas, J Allanson… - Communications …, 2022 - nature.com
The human brain entertains rich spatiotemporal dynamics, which are drastically
reconfigured when consciousness is lost due to anaesthesia or disorders of consciousness …

[HTML][HTML] Dynamic brain fluctuations outperform connectivity measures and mirror pathophysiological profiles across dementia subtypes: a multicenter study

S Moguilner, AM García, YS Perl, E Tagliazucchi… - Neuroimage, 2021 - Elsevier
From molecular mechanisms to global brain networks, atypical fluctuations are the hallmark
of neurodegeneration. Yet, traditional fMRI research on resting-state networks (RSNs) has …

Nonequilibrium brain dynamics as a signature of consciousness

Y Sanz Perl, H Bocaccio, C Pallavicini, I Pérez-Ipiña… - Physical Review E, 2021 - APS
The cognitive functions of human and nonhuman primates rely on the dynamic interplay of
distributed neural assemblies. As such, it seems unlikely that cognition can be supported by …

Whole-brain turbulent dynamics predict responsiveness to pharmacological treatment in major depressive disorder

A Escrichs, Y Sanz Perl, PM Fisher… - Molecular …, 2024 - nature.com
Depression is a multifactorial clinical syndrome with a low pharmacological treatment
response rate. Therefore, identifying predictors of treatment response capable of providing …

Towards an extended taxonomy of information dynamics via integrated information decomposition

PAM Mediano, FE Rosas, AI Luppi… - arXiv preprint arXiv …, 2021 - arxiv.org
Complex systems, from the human brain to the global economy, are made of multiple
elements that interact in such ways that the behaviour of thewhole'often seems to be more …