Adverse childhood experiences and lifelong health

ZA Bhutta, S Bhavnani, TS Betancourt, M Tomlinson… - Nature Medicine, 2023 - nature.com
With the advent of the sustainable development goals, the field of global child health has
shifted its focus from reducing mortality to improving health, nutrition and development …

Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders

Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of developing mental disorders in later life. However, no review has …

Psychoneuroimmunology: An introduction to immune-to-brain communication and its implications for clinical psychology

JE Bower, KR Kuhlman - Annual Review of Clinical Psychology, 2023 - annualreviews.org
Research conducted over the past several decades has revolutionized our understanding of
the role of the immune system in neural and psychological development and function across …

Psychological stress during childhood and adolescence and its association with inflammation across the lifespan: A critical review and meta-analysis.

JJ Chiang, PH Lam, E Chen, GE Miller - Psychological Bulletin, 2022 - psycnet.apa.org
Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

Adverse childhood experiences and severity levels of inflammation and depression from childhood to young adulthood: a longitudinal cohort study

E Iob, R Lacey, V Giunchiglia, A Steptoe - Molecular psychiatry, 2022 - nature.com
Adverse childhood experiences (ACEs) are associated with depression and systemic
inflammation in adults. However, limited longitudinal research has tested these relationships …

Association of childhood adversity with morbidity and mortality in US adults: a systematic review

LR Grummitt, NT Kreski, SG Kim, J Platt… - JAMA …, 2021 - jamanetwork.com
Importance Childhood adversity (CA) is a powerful determinant of long-term physical and
mental health that is associated with elevated risk for chronic disease and psychopathology …

[HTML][HTML] Childhood adversity and vagal regulation: A systematic review and meta-analysis

C Wesarg, AL Van den Akker, NYL Oei… - Neuroscience & …, 2022 - Elsevier
Childhood adversity (CA) is associated with increased risk for physical and mental health
problems, with alterations in vagal regulation (an aspect of autonomic functioning indexed …

[HTML][HTML] The long-term association of adverse childhood experiences with C-reactive protein and hair cortisol: cumulative risk versus dimensions of adversity

E Iob, R Lacey, A Steptoe - Brain, behavior, and immunity, 2020 - Elsevier
Background Exposure to adverse childhood experiences (ACEs) may lead to stress-induced
upregulation of inflammatory and neuroendocrine processes. However, it remains unclear …

The interaction between psychological stress and iron status on early-life neurodevelopmental outcomes

BM Reid, MK Georgieff - Nutrients, 2023 - mdpi.com
This review presents evidence from animal and human studies demonstrating the possible
connection and significant impact of poor iron status and psychological distress on …

Early life maltreatment and resting-state heart rate variability: A systematic review and meta-analysis

C Sigrist, I Mürner-Lavanchy, SKV Peschel… - … & biobehavioral reviews, 2021 - Elsevier
Recent focus on the consequences of early life adversity (ELA) in neurobiological research
led to a variety of findings suggesting alterations in several physiological systems, such as …