MicroRNA-based diagnosis and therapy
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …
expression. Alteration in miRNA expression results in changes in the profile of genes …
Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy
G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …
New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
The liquid biopsy in the management of colorectal cancer patients: Current applications and future scenarios
The term liquid biopsy refers to the analysis of biomarkers in any body fluid, including blood,
urine and cerebrospinal fluid. In cancer, liquid biopsy testing allows the analysis of tumor …
urine and cerebrospinal fluid. In cancer, liquid biopsy testing allows the analysis of tumor …
Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer
Y Li, Z Sun, B Liu, Y Shan, L Zhao, L Jia - Cell death & disease, 2017 - nature.com
Metastasis is a multistep molecular network process, which is the major cause of death in
patients with colorectal cancer (CRC). MicroRNAs (miRNAs) play pivotal roles in …
patients with colorectal cancer (CRC). MicroRNAs (miRNAs) play pivotal roles in …
MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer
L Cekaite, PW Eide, GE Lind, RI Skotheim… - Oncotarget, 2015 - pmc.ncbi.nlm.nih.gov
Gene expression is in part regulated by microRNAs (miRNAs). This review summarizes the
current knowledge of miRNAs in colorectal cancer (CRC); their role as growth regulators, the …
current knowledge of miRNAs in colorectal cancer (CRC); their role as growth regulators, the …
MicroRNAs and colorectal cancer chemoresistance: New solution for old problem
Background Colorectal cancer (CRC) is one of the most common gastrointestinal
malignancies with a significant mortality rate. Despite the great advances in cancer …
malignancies with a significant mortality rate. Despite the great advances in cancer …
[HTML][HTML] MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of β-catenin signaling
Background Distant metastasis is the major cause of cancer-related death, and epithelial-to-
mesenchymal transition (EMT) has a critical role in this process. Accumulating evidence …
mesenchymal transition (EMT) has a critical role in this process. Accumulating evidence …
MicroRNA dysregulation as a prognostic biomarker in colorectal cancer
Colorectal cancer (CRC) is one of the most potentially curable cancers, yet it remains the
fourth most common overall cause of cancer death worldwide. The identification of robust …
fourth most common overall cause of cancer death worldwide. The identification of robust …
A novel saliva-based miRNA signature for colorectal cancer diagnosis
Ó Rapado-González, B Majem… - Journal of clinical …, 2019 - mdpi.com
Salivary microRNAs (miRNAs) are of high interest as diagnostic biomarkers for non-oral
cancer. However, little is known about their value for colorectal cancer (CRC) detection. Our …
cancer. However, little is known about their value for colorectal cancer (CRC) detection. Our …