As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Tumor-infiltrating dendritic cells (DCs) assume varied functional states that impact anti-tumor
immunity. To delineate the DC states associated with productive anti-tumor T cell immunity …

Conventional dendritic cells (cDCs) are professional antigen-presenting cells that control the
adaptive immune response. Their subsets and developmental origins have been intensively …

Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to
their unique ability to initiate T cell responses and direct their differentiation into effector …

Dendritic cells (DCs) can be viewed as translators between innate and adaptive immunity.
They integrate signals derived from tissue infection or damage and present processed …

During wound healing and surgical implantation, the body establishes a delicate balance
between immune activation to fight off infection and clear debris and immune tolerance to …

Differentiation of proinflammatory CD4+ conventional T cells (T conv) is critical for productive
antitumor responses yet their elicitation remains poorly understood. We comprehensively …

Dendritic cells are powerful antigen-presenting cells that are essential for the priming of T
cell responses. In addition to providing T-cell-receptor ligands and co-stimulatory molecules …

Abstract T helper 2 (TH 2) cells orchestrate protective type 2 immune responses, such as
those that target helminths and facilitate tissue repair, but also contribute to chronic …