T cells for viral infections after allogeneic hematopoietic stem cell transplant

CM Bollard, HE Heslop - Blood, The Journal of the American …, 2016 - ashpublications.org
Despite recent advances in the field of allogeneic hematopoietic stem cell transplantation
(HSCT), viral infections are still a major complication during the period of immune …

Virus-specific T-cell banks for'off the shelf'adoptive therapy of refractory infections

RJ O'Reilly, S Prockop, AN Hasan, G Koehne… - Bone marrow …, 2016 - nature.com
Adoptive immunotherapy with transplant donor-derived virus-specific T cells has emerged
as a potentially curative approach for the treatment of drug-refractory EBV+ lymphomas as …

Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia

DT Teachey, SF Lacey, PA Shaw, JJ Melenhorst… - Cancer discovery, 2016 - AACR
Chimeric antigen receptor (CAR)–modified T cells with anti-CD19 specificity are a highly
effective novel immune therapy for relapsed/refractory acute lymphoblastic leukemia …

Early cytomegalovirus reactivation remains associated with increased transplant-related mortality in the current era: a CIBMTR analysis

P Teira, M Battiwalla, M Ramanathan… - Blood, The Journal …, 2016 - ashpublications.org
Single-center studies have reported an association between early (before day 100)
cytomegalovirus (CMV) reactivation and decreased incidence of relapse for acute myeloid …

Transfer of minimally manipulated CMV-specific T cells from stem cell or third-party donors to treat CMV infection after allo-HSCT

M Neuenhahn, J Albrecht, M Odendahl, F Schlott… - Leukemia, 2017 - nature.com
Cytomegalovirus (CMV) infection is a common, potentially life-threatening complication
following allogeneic hematopoietic stem cell transplantation (allo-HSCT). We assessed …

Third-party cytomegalovirus-specific T cells improved survival in refractory cytomegalovirus viremia after hematopoietic transplant

SE Prockop, A Hasan, E Doubrovina… - The Journal of …, 2023 - Am Soc Clin Investig
Background Refractory CMV viremia and disease are associated with significant morbidity
and mortality in recipients of hematopoietic stem cell transplant (HCT). Methods In phase I/II …

Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation

K Chen, MP Cheng, SP Hammond, H Einsele… - Blood …, 2018 - ashpublications.org
Patients treated with allogeneic hematopoietic cell transplantation (HCT) are at risk of
cytomegalovirus (CMV) reactivation and disease, which results in increased morbidity and …

Viral infections in HSCT: detection, monitoring, clinical management, and immunologic implications

C Annaloro, F Serpenti, G Saporiti, G Galassi… - Frontiers in …, 2021 - frontiersin.org
In spite of an increasing array of investigations, the relationships between viral infections
and allogeneic hematopoietic stem cell transplantation (HSCT) are still controversial, and …

Virus-specific T cells for the immunocompromised patient

A Houghtelin, CM Bollard - Frontiers in immunology, 2017 - frontiersin.org
While progress has been made in the treatment of both hematologic cancers and solid
tumors, chemorefractory or relapsed disease often portends a dismal prognosis, and …

Immunocompromised host section: Adoptive T-cell therapy for dsDNA viruses in allogeneic hematopoietic cell transplant recipients

CS Walti, C Stuehler, D Palianina… - Current Opinion in …, 2022 - journals.lww.com
Immunocompromised host section: Adoptive T-cell therapy for... : Current Opinion in
Infectious Diseases Immunocompromised host section: Adoptive T-cell therapy for dsDNA …