Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The
current standard of care involves surgical resection (if possible) followed by concomitant …

Glioblastoma is the most common malignant primary brain tumor in adults and is almost
invariably fatal. Despite our growing understanding of the various mechanisms underlying …

CNS tumors remain among the deadliest forms of cancer, resisting conventional and new
treatment approaches, with mortality rates staying practically unchanged over the past 30 …

Autologous T cells genetically engineered to express chimeric antigen receptor (CAR) have
shown promising outcomes and emerged as a new curative option for hematological …

Glioblastoma is the most common primary brain tumor and has a dismal prognosis. The
development of central necrosis represents a tipping point in the evolution of these tumors …

Glioblastoma (GBM) is a devastating adult brain cancer with high rates of recurrence and
treatment resistance. Cellular heterogeneity and extensive invasion of surrounding brain …

Simple Summary Clinical trials in glioblastoma (GBM) using CAR-T cells have not yielded
tangible results. However, clinical and immunological observations from the trials have …

Tumor recurrence is the main challenge in glioblastoma (GBM) treatment. Gold standard
therapy temozolomide (TMZ) is known to induce upregulation of IL8/CXCL2/CXCR2 …

Ferroptosis is a type of regulated cell death that plays an essential role in various brain
diseases, including cranial trauma, neuronal diseases, and brain tumors. It has been …

Due to their superb light absorption and photostability conjugated polymer nanoparticles are
promising photosensitizers (PS) for their use in Photodynamic therapy (PDT). Recently, we …