Pathophysiology of the different clinical phenotypes of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)

E Dziadkowiak, M Waliszewska-Prosół… - International Journal of …, 2021 - mdpi.com
Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common form of
autoimmune polyneuropathy. It is a chronic disease and may be monophasic, progressive or …

Proteomics profiling and machine learning in nusinersen-treated patients with spinal muscular atrophy

C Panicucci, E Sahin, M Bartolucci, S Casalini… - Cellular and Molecular …, 2024 - Springer
Aim The availability of disease-modifying therapies and newborn screening programs for
spinal muscular atrophy (SMA) has generated an urgent need for reliable prognostic …

Overall role of contactins expression in neurodevelopmental events and contribution to neurological disorders

A Bizzoca, E Jirillo, P Flace… - CNS & Neurological …, 2023 - ingentaconnect.com
Background: Neurodegenerative disorders may depend upon a misregulation of the
pathways which sustain neurodevelopmental control. In this context, this review article …

[PDF][PDF] Alzheimer's disease treated with autologous and allogeneic telomerase-positive stem cells

HE Young, MO Speight - Stem Cells Regen Med, 2021 - researchgate.net
Alzheimer's disease is an insidious and progressive loss of balance and cognitive memories
from present time to distant past that occurs in reverse chronological order. While the cause …

Association between serum multi-protein biomarker profile and real-world disability in multiple sclerosis

W Zhu, C Chen, L Zhang, T Hoyt, E Walker… - Brain …, 2024 - academic.oup.com
Few studies examined blood biomarkers informative of patient-reported outcome (PRO) of
disability in people with multiple sclerosis (MS). We examined the associations between …

Autoimmune nodopathy with anti-contactin 1 antibody characterized by cerebellar dysarthria: a case report and literature review

J Chen, L Liu, H Zhu, J Han, R Li, X Gong… - Frontiers in …, 2024 - frontiersin.org
Background Autoimmune nodopathy (AN) has emerged as a novel diagnostic category that
is pathologically different from classic chronic inflammatory demyelinating polyneuropathy …

The preferential effect of Clemastine on F3/Contactin-1/Notch-1 compared to Jagged-1/Notch-1 justifies its remyelinating effect in an experimental model of multiple …

SM Ibrahim, AS Kamel, KA Ahmed… - International …, 2024 - Elsevier
Clemastine (CLM) is repurposed to enhance remyelination in multiple sclerosis (MS)
patients. CLM blocks histamine and muscarinic receptors as negative regulators to …

Neonatal Hypoxia-Ischemia alters Brain-Derived Contactin-2-Positive Extracellular Vesicles in the Mouse Plasma

SX Liu, DGV Calderon, ZL Maxim, MM Beeson, R Rao… - Neuroscience, 2024 - Elsevier
Neonatal encephalopathy (NE) impairs white matter development and results in long-term
neurodevelopmental deficits. Leveraging prior findings of altered neuronal proteins carried …

Assessment of the protective and ameliorative impact of quercetin nanoparticles against neuronal damage induced in the hippocampus by acrolein

SM Sanad, SE Nassar, R Farouk - Beni-Suef University Journal of Basic …, 2024 - Springer
Background The most frequent kind of dementia in the senior population is Alzheimer's
disease (AD). Antioxidant quercetin has a low bioavailability. The bioavailability of quercetin …

Anti-CNTN-1 autoimmune nodopathies with dysarthria at onset-a case report and literature review

J Chen, L Liu, H Zhu, R Li, H Li, X Gong, H Fu, J Long… - 2023 - researchsquare.com
BACKGROUND: Anti-CNTN-1 autoimmune nodopathies (AN) is a new and rare diagnosis of
peripheral neuropathy proposed by the European Society of Neurology in recent years …