Given the high toxicity of inorganic inhibitors, organic substances, primarily heterocycles,
have been proven to be one of the most efficient, cost-effective, and practical alternatives …

The quest for sustainable ways to introduce diverse functional groups onto complex
scaffolds has made directed transition metal-catalysed C–H functionalization reactions a …

The landscape of organic synthesis has changed in the last two decades, especially in
areas such as pharmaceutical synthesis and large-scale industrial synthesis. The progress …

In a ball mill, FeBr3‐catalyzed intramolecular amidations lead to 3, 4‐dihydro‐2 (1H)‐
quinolinones in good to almost quantitative yields. The reactions do not require a solvent …

The combination of visible light irradiation and Pd-catalysis has been practically employed
for the C–H alkylation reactions of naphthylamines and α-diazo esters, leading to the …

An expedient, mechanochemical, operationally simple protocol is reported for the Rh-
catalysed C–H methylation of (hetero) arenes under solvent-free conditions without the use …

Oxidative reactions provide an effective strategy for phenol transformation via conjugated
addition, C–H functionalization, cyclization reactions, etc. It has enabled broad utilization of …

Directed C–H arylations have proven to be some of the most advantageous strategies for the
synthesis of biaryls. However, their sensitivity toward steric hindrance is a key limitation …

The replacement of conventional organic solvents by the so-called “green solvents” is a
usual approach to more sustainable chemical processes. Supercritical carbon dioxide …

This review introduces the application of a transient directing strategy in cyclization reactions
via C–H activation. The types of cyclization reactions include C–H activation/intramolecular …