[HTML][HTML] The role of lipoxygenases in pathophysiology; new insights and future perspectives
R Mashima, T Okuyama - Redox biology, 2015 - Elsevier
Lipoxygenases (LOXs) are dioxygenases that catalyze the formation of corresponding
hydroperoxides from polyunsaturated fatty acids such as linoleic acid and arachidonic acid …
hydroperoxides from polyunsaturated fatty acids such as linoleic acid and arachidonic acid …
Clinical and pathologic perspectives on aspirin sensitivity and asthma
DD Stevenson, A Szczeklik - Journal of Allergy and Clinical Immunology, 2006 - Elsevier
Aspirin and other nonsteroidal anti-inflammatory drugs that inhibit COX-1 induce unique
nonallergic reactions, consisting of attacks of rhinitis and asthma. These hypersensitivity …
nonallergic reactions, consisting of attacks of rhinitis and asthma. These hypersensitivity …
Influence of leukotriene pathway polymorphisms on response to montelukast in asthma
JJ Lima, S Zhang, A Grant, L Shao… - American journal of …, 2006 - atsjournals.org
Rationale: Interpatient variability in montelukast response may be related to variation in
leukotriene pathway candidate genes. Objective: To determine associations between …
leukotriene pathway candidate genes. Objective: To determine associations between …
Cysteinyl‐leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends
Abstract Cysteinyl‐leukotrienes (cysteinyl‐LTs), that is, LTC4, LTD4, and LTE4, trigger
contractile and inflammatory responses through the specific interaction with G protein …
contractile and inflammatory responses through the specific interaction with G protein …
Current perspective on eicosanoids in asthma and allergic diseases: EAACI Task Force consensus report, part I
M Sokolowska, GE Rovati, Z Diamant, E Untersmayr… - Allergy, 2021 - Wiley Online Library
Eicosanoids are biologically active lipid mediators, comprising prostaglandins, leukotrienes,
thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to …
thromboxanes, and lipoxins, involved in several pathophysiological processes relevant to …
Elucidating asthma phenotypes and endotypes: progress towards personalized medicine
M Desai, J Oppenheimer - Annals of Allergy, Asthma & Immunology, 2016 - Elsevier
Over time, there has been a shift in the paradigm of asthma, from a single-disease concept
toward a greater recognition of asthma as a complex, chronic disease with marked clinical …
toward a greater recognition of asthma as a complex, chronic disease with marked clinical …
[图书][B] Drug hypersensitivity
WJ Pichler - 2007 - books.google.com
A Karger'Publishing Highlights 1890-2015'title Drug hypersensitivities are immune-mediated
reactions characterized by exanthems, fever and internal organ involvement. They represent …
reactions characterized by exanthems, fever and internal organ involvement. They represent …
Leukotriene pathway genetics and pharmacogenetics in allergy
Leukotrienes (LT) are biologically active lipid mediators known to be involved in allergic
inflammation. Leukotrienes have been shown to mediate diverse features of allergic …
inflammation. Leukotrienes have been shown to mediate diverse features of allergic …
ALOX5 variants associated with susceptibility to human pulmonary tuberculosis
Abstract The 5-lipoxygenase (ALOX5)-derived lipid mediators leukotrienes and lipoxins
have regulatory functions in inflammation by modulating activities of immune cells and …
have regulatory functions in inflammation by modulating activities of immune cells and …
Genetics and phenotyping in chronic sinusitis
SC Payne, L Borish, JW Steinke - Journal of allergy and clinical …, 2011 - Elsevier
Chronic sinusitis with nasal polyposis historically has been treated as a single monolithic
clinical disorder. Just as asthma is now accepted as numerous heterogeneous diseases …
clinical disorder. Just as asthma is now accepted as numerous heterogeneous diseases …