The malaria parasite life cycle alternates between two hosts: a vertebrate and the female
Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for …

Apicomplexan parasites, such as human malaria parasites, have complex lifecycles
encompassing multiple and diverse environmental niches. Invading, replicating, and …

Malaria is caused by infection of the erythrocytes by the parasites Plasmodium. Inside the
erythrocytes, the parasites multiply via schizogony, an unconventional cell division mode …

In malaria parasites, evolution of parasitism has been linked to functional optimisation.
Despite this optimisation, most members of a calcium-dependent protein kinase (CDPK) …

Plasmodium parasites are obligate intracellular protozoa and causative agents of malaria,
responsible for half a million deaths each year. The lifecycle progression of the parasite is …

Apicomplexan parasites rely on tubulin structures throughout their cell and life cycles,
particularly in the polymerization of spindle microtubules to separate the replicated nucleus …

The inner membrane complex (IMC) is a defining feature of apicomplexan parasites, which
confers stability and shape to the cell, functions as a scaffolding compartment during the …

Ubiquitylation is a common post translational modification of eukaryotic proteins and in the
human malaria parasite, Plasmodium falciparum (Pf) overall ubiquitylation increases in the …

With emerging resistance to frontline treatments, it is vital that new antimalarial drugs are
identified to target Plasmodium falciparum. We have recently described a compound …

The myosin superfamily comprises of actin‐dependent eukaryotic molecular motors
important in a variety of cellular functions. Although well studied in many systems …