In this review, transition metal-catalyzed methodologies and applications that exploit C–C
bond cleavage of vinylcyclopropanes (VCPs) are summarized with a focus on cycloaddition …

In this review, synthetic and mechanistic aspects of key methodologies that exploit C–C
single-bond cleavage of strained ring systems are highlighted. The focus is on transition …

The cleavage and reorganization of carbon− carbon bonds is an industrial key technology
for crude oil refining, carried out on a massive scale. In contrast, C− C bond cleavage …

The transition-metal-catalyzed “cut and sew” transformation has recently emerged as a
useful strategy for preparing complex molecular structures. After oxidative addition of a …

Vinylcyclopropane (VCP) derivatives participate in a variety of transition-metal-catalyzed
multicomponent cycloadditions to produce five-to eight-membered carbocycles. Various …

Activated cyclopropanes show versatile reactivity and are therefore powerful building blocks
in organic chemistry and natural product synthesis. This review focuses on recent …

A novel iodine promoted [1+ 3+ 2] cleavage cyclization reaction for the synthesis of 1H-
pyrazolo [3, 4-b] pyridines from aryl methyl ketones, 5-aminopyrazoles and enaminones has …

Vinyl cyclopropanes are amongst the most useful building blocks in organic synthesis. Their
easy opening and capacity to generate dipoles have been exploited for the synthesis of …

Previously, we developed a rhodium-catalyzed [5+ 2+ 1] cycloaddition of ene–
vinylcyclopropanes (ene–VCPs) and carbon monoxide to synthesize eight-membered …

Covering: 2000–2018 In this review, we highlight recent examples of natural product total
syntheses employing transition metal-mediated/catalyzed carbonylative cyclization …