Early clearance (EC) is the successful eradication of inhaled M ycobacterium tuberculosis
before an adaptive immune response develops. Evidence for EC comes from case contact …

HIV is the top and tuberculosis is the second leading cause of death from infectious disease
worldwide, with an estimated 8.7 million incident cases of tuberculosis and 2.5 million new …

While a third of the world carries the burden of tuberculosis, disease control has been
hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective …

Human immunodeficiency virus type 1 (HIV-1) infection is a chronic disease without a known
cure. The advent of effective antiretroviral therapy (ART) has enabled people with HIV …

Although combined antiretroviral therapy (cART) is effective in inhibiting human
immunodeficiency virus type 1 (HIV-1) replication, it does not eradicate the virus because …

Background Tuberculosis (TB) and AIDS are the leading causes of infectious diseases
death worldwide. Here, we investigated the relationship between from single nucleotide …

Problem: Only a small proportion of HPV+ women develop virus‐associated lesions and
cervical cancer, suggesting that other factors are involved in HPV+ keratinocyte …

The inflammasome is a cytoplasmic multiprotein complex responsible for the activation of
inflammatory caspases (caspase-1,-4, and-5) in response to pathogen-and/or damage …

Purinergic receptors and nucleotide-binding domain leucine-rich repeat containing (NLR)
proteins have been shown to control viral infection. Here, we show that the NLR family …

Introduction Human immunodeficiency virus type 1 (HIV-1) causes a chronic, incurable
infection leading to immune activation and chronic inflammation in people with HIV-1 (PWH) …