Itch is a common sensory experience that is prevalent in patients with inflammatory skin
diseases, as well as in those with systemic and neuropathic conditions. In patients with …

Itch, in particular chronic forms, has been widely recognized as an important clinical
problem, but much less is known about the mechanisms of itch in comparison with other …

This is the English version of the Clinical Practice Guidelines for the Management of Atopic
Dermatitis 2021. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with …

Atopic dermatitis (AD) displays different clinical symptoms, progress, and response to
treatment during early infancy and after childhood. After the childhood period, itch appears …

Itch is an aversive sensation that evokes a desire to scratch. Paradoxically, scratching the
itch also produces a hedonic experience. The specific brain circuits processing these …

All humans experience itch in the course of their life. Even a discussion on the topic of itch or
seeing people scratch can evoke the desire to scratch. These events are coined “contagious …

The itch-scratching cycle is mediated by neural dynamics in the brain. However, our
understanding of the neural dynamics during this cycle remains limited. In this study, we …

Itch is an unpleasant somatic sensation with the desire to scratch, and it consists of sensory,
affective, and motivational components. Acute itch serves as a critical protective mechanism …

Clinically, it has been reported that atopic dermatitis (AD) has been linked with negative
emotional problems such as depression and anxiety, thereby reducing the quality of life, but …

Scratching evokes a rewarding and pleasurable sensation, particularly in chronic itch
patients. To date, no study has investigated the cerebral activity during scratching in chronic …