Covering: 2015 to 2022 Staphylococcus aureus (S. aureus) is responsible for several
community and hospital-acquired infections with life-threatening complications such as …

In this work, we report the isolation and detailed functional characterization for the new non-
ribosomally synthesized antibiotic 5812-A/C, which was derived from metabolites of …

The continued rise of antibiotic resistance is a global concern that threatens to undermine
many aspects of modern medical practice. Key to addressing this threat is the discovery and …

The continuing rise of antibiotic resistance, particularly among Gram-negative pathogens,
threatens to undermine many aspects of modern medical practice. To address this threat …

Polysubstituted phenylisoxazoles were designed and synthesized to discover new
antibacterial agents via [3+ 2] cycloaddition. Thirty-five compounds with a phenylisoxazole …

The prevalence of drug‐resistant bacterial pathogens foreshadows a healthcare crisis.
Calcium‐dependent antibiotics (CDAs) are promising candidates to combat infectious …

Background In recent years, new drugs for the treatment of various diseases, thereby the
emergence of antimicrobial resistance tremendously increased because of the increased …

Cell wall antibiotics are important tools in our fight against Gram-positive pathogens, but
many strains become increasingly resistant against existing drugs. Laspartomycin C is a …

摘要拉斯帕托霉素C (Laspartomycin C, LspC) 是被最廣泛研究的鈣依賴型抗生素(Calcium-
dependent antibiotic, CDA) 之一. 在之前已有關於LspC 的晶體研究, 在研究中已經證實了LspC …

The continued rise of antibiotic resistance is a global concern that threatens to undermine
many aspects of modern medical practice. Key to addressing this threat is the discovery and …