Postnatal maturation of breathing stability and loop gain: the role of carotid chemoreceptor development
BA Edwards, SA Sands, PJ Berger - Respiratory physiology & …, 2013 - Elsevier
Any general model of respiratory control must explain a puzzling array of breathing patterns
that are observed during the course of a lifetime. Particular challenges are to understand …
that are observed during the course of a lifetime. Particular challenges are to understand …
Congestive heart failure and central sleep apnea
His breathing was very particular: he would cease breathing for twenty or thirty seconds, and
then begin to breathe softly, which increased until he breathed extremely strong, or rather …
then begin to breathe softly, which increased until he breathed extremely strong, or rather …
Loop gain as a means to predict a positive airway pressure suppression of Cheyne-Stokes respiration in patients with heart failure
Rationale: Patients with heart failure (HF) and Cheyne-Stokes respiration or periodic
breathing (PB) often demonstrate improved cardiac function when treatment with continuous …
breathing (PB) often demonstrate improved cardiac function when treatment with continuous …
Periodic breathing and oxygen supplementation in Chilean miners at high altitude (4200 m)
FA Moraga, D Jiménez, JP Richalet, M Vargas… - Respiratory Physiology …, 2014 - Elsevier
Our objective was to determine the nocturnal ventilatory pattern and characterize the effect
of oxygen enrichment on nocturnal ventilatory pattern and sleep quality in miners exposed to …
of oxygen enrichment on nocturnal ventilatory pattern and sleep quality in miners exposed to …
Model-based characterization of ventilatory stability using spontaneous breathing
Cyclic ventilatory instabilities are widely attributed to an increase in the sensitivity or loop
gain of the chemoreflex feedback loop controlling ventilation. A major limitation in the …
gain of the chemoreflex feedback loop controlling ventilation. A major limitation in the …
Continuous positive airway pressure reduces loop gain and resolves periodic central apneas in the lamb
Continous positive airway pressure (CPAP) is used to treat infant respiratory distress
syndrome and apnea of prematurity, but its mode of action is not fully understood. We …
syndrome and apnea of prematurity, but its mode of action is not fully understood. We …
Increased peripheral chemosensitivity via dopaminergic manipulation promotes respiratory instability in lambs
Periodic breathing (PB) is an instability of the respiratory control system believed to be
mediated principally by the peripheral chemoreceptors. We hypothesised that domperidone …
mediated principally by the peripheral chemoreceptors. We hypothesised that domperidone …
Assessing ventilatory instability using the response to spontaneous sighs during sleep in preterm infants
Abstract Study Objectives Periodic breathing (PB) is common in newborns and is an obvious
manifestation of ventilatory control instability. However, many infants without PB may still …
manifestation of ventilatory control instability. However, many infants without PB may still …
A pilot study of sleep, cognition, and respiration under 4 weeks of intermittent nocturnal hypoxia in adult humans
MD Weiss, R Tamisier, J Boucher, M Lynch, G Gilmartin… - Sleep medicine, 2009 - Elsevier
STUDY OBJECTIVES: A pilot study to examine the effects of intermittent nocturnal hypoxia
on sleep, respiration and cognition in healthy adult humans. METHODS: Participants were …
on sleep, respiration and cognition in healthy adult humans. METHODS: Participants were …
Postnatal development of periodic breathing cycle duration in term and preterm infants
Previous studies of the maturation of periodic breathing cycle duration (PCD) with postnatal
age in infants have yielded conflicting results. PCD is reported to fall in term infants over the …
age in infants have yielded conflicting results. PCD is reported to fall in term infants over the …