A molecular perspective on sirtuin activity

CSS Teixeira, NM Cerqueira, P Gomes… - International Journal of …, 2020 - mdpi.com
The protein acetylation of either the α-amino groups of amino-terminal residues or of internal
lysine or cysteine residues is one of the major posttranslational protein modifications that …

Selective inhibitors of histone deacetylase 10 (HDAC-10)

E Pojani, D Barlocco - Current Medicinal Chemistry, 2022 - ingentaconnect.com
Histone acetylation balance is one epigenetic mechanism controlling gene expression
associated with disease progression. It has been observed that histone deacetylase 10 …

Dietary and metabolic compounds affecting covalent histone modifications

GW Davison - Handbook of Epigenetics, 2023 - Elsevier
DNA and histones are packed together to contain heritable genetic information in the form of
chromatin, and while terminal tails generally protrude from the nucleosome core particles …

Unique Posttranslational Modification Sites of Acetylation, Citrullination, Glutarylation, and Phosphorylation Are Found to Be Specific to the Proteins Partitioned in the …

H Phukan, A Sarma, DAB Rex, AB Rai, TSK Prasad… - ACS …, 2022 - ACS Publications
Posttranslational modifications (PTMs) are decisive factors in the structure, function, and
localization of proteins in prokaryotic and eukaryotic organisms. However, prokaryotic …

Tumor Associated Macrophages (TAMs) a pivotal orchestrator in cancer-related inflammation and a new important target in cancer-therapy

S Mola - 2021 - iris.uniupo.it
Macrophages are pivotal orchestrators of tumor-promoting inflammation and promising
targets for new anti-cancer therapies. To identify new molecular players underlying their pro …