Ocular diseases can deteriorate vision to the point of blindness and thus can have a major
impact on the daily life of an individual. Conventional therapies are unable to provide …

Chitosan (CS) is a hemi-synthetic cationic linear polysaccharide produced by the
deacetylation of chitin. CS is non-toxic, highly biocompatible, and biodegradable, and it has …

This review article is an updated overview on lipid-polymer hybrid nanoparticles (LPHNs)
including the various types of LPHNs polymers used in their preparation, various methods of …

Astaxanthin (AXT) is one of the most important fat-soluble carotenoids that have abundant
and diverse therapeutic applications namely in liver disease, cardiovascular disease, cancer …

Various strategies for ocular drug delivery are considered; from basic formulation techniques
for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug …

Recent years have witnessed a boom in ocular nanomedicine research with a number of
lipid-based nanocarriers such as liposomes, niosomes, cubosomes, nanoemulsions, solid …

The most important risk associated with glaucoma is the onset and progression of
intraocular pressure. The objective of this study was to formulate in situ gel of chitosan …

The efficacy of conventional ocular formulations is limited by poor corneal retention and
permeation, resulting in low ocular bioavailability. Mucoadhesive chitosan (CS) …

Dry eye disease (DED) is an emerging health problem affecting millions of individuals every
year. The current treatments for DED include lubricating eye drops and anti-inflammatory …

The objective of research was to develop a novel pH-triggered polymeric nanoparticulate in
situ gel (NP-ISG) for ophthalmic delivery of acetazolamide (ACZ) to enhance the conjunctival …