The Martini model, a coarse‐grained force field for molecular dynamics simulations, has
been around for nearly two decades. Originally developed for lipid‐based systems by the …

Roughly one quarter of all genes code for integral membrane proteins that are inserted into
the plasma membrane of prokaryotes or the endoplasmic reticulum membrane of …

Most membrane proteins are synthesized on endoplasmic reticulum (ER)-bound ribosomes
docked at the translocon, a heterogeneous ensemble of transmembrane factors operating …

The molecular details involved in the folding, dynamics, organization, and interaction of
proteins with other molecules are often difficult to assess by experimental techniques …

Abstract Energy-coupling factor (ECF)-type transporters mediate the uptake of micronutrients
in many bacteria. They consist of a substrate-translocating subunit (S-component) and an …

Multipass membrane proteins contain two or more α-helical transmembrane domains
(TMDs) that span the lipid bilayer. They are inserted cotranslationally into the prokaryotic …

Ribosomes interact with a variety of different protein biogenesis factors that guide newly
synthesized proteins to their native 3D shapes and cellular localization. Depending on the …

During legume-rhizobia symbiosis, differentiation of the symbiosome (engulfed intracellular
rhizobia) is necessary for successful nitrogen fixation. To control symbiosome differentiation …

Membrane thinning by rhomboid proteins has been proposed to reduce hydrophobic
mismatch, providing a unique environment for important functions ranging from …

The disassembly of integrin-containing focal adhesions (FAs) at mitotic entry is essential for
cell rounding, mitotic retraction fibre formation, bipolar spindle positioning and chromosome …