Domoic acid (DA), the causative agent for the human syndrome Amnesic Shellfish
Poisoning (ASP), is a potent, naturally occurring neurotoxin produced by common marine …

Postoperative cognitive dysfunction (POCD) has been hypothesized to be mediated by
surgery-induced inflammatory processes, which may influence neuronal functioning either …

Functional expression of voltage-gated Na+ channels (VGSCs) has been demonstrated in
multiple cancer cell types where channel activity induces invasive activity. The signaling …

Chondrosarcomas are a type of primary malignant bone cancer, with a potent capacity for
local invasion and distant metastasis. Brain-derived neurotrophic factor (BDNF) is commonly …

It is now well established that many of society's most devastating and costly neurological
diseases and disorders arise from trauma at, or shortly after birth. In some cases deficits are …

Abstract Effects of withdrawal from ethanol drinking in chronic intermittent ethanol vapor
(CIE)-exposed dependent rats and air-exposed nondependent rats on proliferation and …

Age is the most prominent risk factor for the development of postoperative cognitive
dysfunction. This study investigated the potential role of anti-inflammatory interleukin (IL)-4 …

A rat model of vascular dementia was used to compare the effects of involuntary exercise
induced by functional electrical stimulation (FES), forced exercise and voluntary exercise on …

γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mature brain but
has the paradoxical property of depolarizing neurons during early development …

Kainate receptors play an important role in the brain. They contribute to postsynaptic
depolarization, modulate the release of neurotransmitters such as GABA and glutamate …