Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives
proteinuria or nephrotic syndrome. In children and young adults, genetic variants in> 50 …

The incidence of idiopathic nephrotic syndrome (NS) is 1· 15–16· 9 per 100 000 children,
varying by ethnicity and region. The cause remains unknown but the pathogenesis of …

Chronic kidney disease (CKD) represents a leading cause of death in the United States.
There is no cure for this disease, with current treatment strategies relying on blood pressure …

Most glomerulonephritides, even the more common types, are rare diseases. They are
nevertheless important since they frequently affect young people, often cannot be cured, and …

Podocytes are highly specialized cells of the kidney glomerulus that wrap around capillaries
and that neighbor cells of the Bowman's capsule. When it comes to glomerular filtration …

Genetic studies of hereditary forms of nephrotic syndrome have identified several proteins
that are involved in regulating the permselective properties of the glomerular filtration …

Podocytes are a major component of the glomerular blood filtration barrier, and alterations to
the morphology of their unique actin-based foot processes (FP) are a common feature of …

Focal segmental glomerulosclerosis (FSGS) is a common glomerular disorder that manifests
clinically with the nephrotic syndrome and has a propensity to recur following kidney …

The prevalence, pathogenesis, predictors, and natural course of patients with recurrent
glomerulonephritis (GN) occurring after kidney transplantation remains incompletely …

Podocyte injury is a hallmark of glomerular diseases; however, the underlying mechanisms
remain unclear. B7-1 is increased in injured podocytes, but its intrinsic role is controversial …