▪ Abstract Synaptic transmission is a dynamic process. Postsynaptic responses wax and
wane as presynaptic activity evolves. This prominent characteristic of chemical synaptic …

Abstract Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004;
10.1152/physrev. 00014.2003.—One of the most significant challenges in neuroscience is to …

Recent studies highlight the implication of innate and adaptive immunity in the
pathophysiology of Alzheimer's disease, and foster immunotherapy as a promising strategy …

Synaptic dysfunction is an early pathological feature of neurodegenerative diseases
associated with Tau, including Alzheimer's disease. Interfering with early synaptic …

Despite being the most abundant synaptic vesicle membrane protein, the function of
synaptophysin remains enigmatic. For example, synaptic transmission was reported to be …

Neuronal communication crucially relies on exocytosis of neurotransmitters from synaptic
vesicles (SVs) which are clustered at synapses. To ensure reliable neurotransmitter release …

SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) are now
generally accepted to be the major players in the final stage of the docking and the …

Microarray expression profiling of prefrontal cortex from matched pairs of schizophrenic and
control subjects and hierarchical data analysis revealed that transcripts encoding proteins …

Synaptic vesicles are organelles with a precisely defined protein and lipid composition,, yet
the molecular mechanisms for the biogenesis of synaptic vesicles are mainly unknown. Here …

Sensory, motor, and cognitive stimuli, resulting from interactions with the environment, play a
key role in optimizing and modifying the neuronal circuitry required for normal brain function …