Drug delivery systems for programmed and on-demand release

P Davoodi, LY Lee, Q Xu, V Sunil, Y Sun, S Soh… - Advanced drug delivery …, 2018 - Elsevier
With the advancement in medical science and understanding the importance of
biodistribution and pharmacokinetics of therapeutic agents, modern drug delivery research …

FDA approved guidance conduits and wraps for peripheral nerve injury: a review of materials and efficacy

S Kehoe, XF Zhang, D Boyd - Injury, 2012 - Elsevier
Several nerve guidance conduits (NGCs) and nerve protectant wraps are approved by the
US Food and Drug Administration (FDA) for clinical use in peripheral nerve repair. These …

Design, clinical translation and immunological response of biomaterials in regenerative medicine

K Sadtler, A Singh, MT Wolf, X Wang… - Nature Reviews …, 2016 - nature.com
The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …

Regeneration of peripheral nerves by nerve guidance conduits: Influence of design, biopolymers, cells, growth factors, and physical stimuli

MD Sarker, S Naghieh, AD McInnes, DJ Schreyer… - Progress in …, 2018 - Elsevier
Injuries to the peripheral nervous system (PNS) cause neuropathies that lead to weakness
and paralysis, poor or absent sensation, unpleasant and painful neuropathies, and impaired …

Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration

X Gu, F Ding, Y Yang, J Liu - Progress in neurobiology, 2011 - Elsevier
Surgical repair of severe peripheral nerve injuries represents not only a pressing medical
need, but also a great clinical challenge. Autologous nerve grafting remains a golden …

[HTML][HTML] Scaffolds for tissue fabrication

PX Ma - Materials today, 2004 - Elsevier
Tissue engineering is an interdisciplinary and multidisciplinary field. It has shown great
promise in generating living alternatives for harvested tissues and organs for transplantation …

Repairing injured peripheral nerves: bridging the gap

R Deumens, A Bozkurt, MF Meek, MAE Marcus… - Progress in …, 2010 - Elsevier
Peripheral nerve injuries that induce gaps larger than 1–2cm require bridging strategies for
repair. Autologous nerve grafts are still the gold standard for such interventions, although …

Stem cell-based tissue engineering with silk biomaterials

Y Wang, HJ Kim, G Vunjak-Novakovic, DL Kaplan - Biomaterials, 2006 - Elsevier
Silks are naturally occurring polymers that have been used clinically as sutures for centuries.
When naturally extruded from insects or worms, silk is composed of a filament core protein …

Recent concepts in biodegradable polymers for tissue engineering paradigms: A critical review

N Iqbal, AS Khan, A Asif, M Yar… - International …, 2019 - journals.sagepub.com
Tissue engineering and regenerative medicine are emerging as future approaches for the
treatment of acute and chronic diseases. Numerous clinical conditions exist today and …

Biomedical engineering strategies for peripheral nerve repair: surgical applications, state of the art, and future challenges

BJ Pfister, T Gordon, JR Loverde… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Damage to the peripheral nervous system is surprisingly common and occurs primarily from
trauma or a complication of surgery. Although recovery of nerve function occurs in many mild …