Therapeutic nanoparticles and their targeted delivery applications

AA Yetisgin, S Cetinel, M Zuvin, A Kosar, O Kutlu - Molecules, 2020 - mdpi.com
Nanotechnology offers many advantages in various fields of science. In this regard,
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …

New advances in in vivo applications of gated mesoporous silica as drug delivery nanocarriers

A García‐Fernández, E Aznar, R Martínez‐Máñez… - Small, 2020 - Wiley Online Library
One appealing concept in the field of hybrid materials is related to the design of gated
materials. These materials are prepared in such a way that the release of chemical or …

Magnetic targeting, tumor microenvironment-responsive intelligent nanocatalysts for enhanced tumor ablation

L Feng, R Xie, C Wang, S Gai, F He, D Yang, P Yang… - ACS …, 2018 - ACS Publications
Therapeutic nanosystems which can be triggered by the distinctive tumor microenvironment
possess great selectivity and safety to treat cancers via in situ transformation of nontoxic …

Hyperthermia and controllable free radical coenhanced synergistic therapy in hypoxia enabled by near-infrared-II light irradiation

J Yang, R Xie, L Feng, B Liu, R Lv, C Li, S Gai, F He… - ACS …, 2019 - ACS Publications
Tumor cell metabolism and tumor blood vessel proliferation are distinct from normal cells.
The resulting tumor microenvironment presents a characteristic of hypoxia, which greatly …

[HTML][HTML] Receptor-mediated targeted drug delivery systems for treatment of inflammatory bowel disease: Opportunities and emerging strategies

P Liu, C Gao, H Chen, CT Vong, X Wu, X Tang… - … Pharmaceutica Sinica B, 2021 - Elsevier
Inflammatory bowel disease (IBD) is a chronic intestinal disease with painful clinical
manifestations and high risks of cancerization. With no curative therapy for IBD at present …

Tumor-specific expansion of oxidative stress by glutathione depletion and use of a fenton nanoagent for enhanced chemodynamic therapy

Q Chen, J Zhou, Z Chen, Q Luo, J Xu… - ACS applied materials & …, 2019 - ACS Publications
Amplifying intracellular oxidative stress effectively destroys cancer cells. In addition, iron-
mediated Fenton reaction converts endogenous H2O2 to produce hypertoxic hydroxyl …

Cancer‐targeted nanomedicine: overcoming the barrier of the protein corona

AK Barui, JY Oh, B Jana, C Kim… - Advanced therapeutics, 2020 - Wiley Online Library
Nanomedicines exploit the unusual physicochemical and biological properties of
nanoparticles, including their nanoscopic size, high surface‐area‐to‐volume ratio, easy …

Artificial engineering of the protein corona at bio-nano interfaces for improved cancer-targeted nanotherapy

S Khan, M Sharifi, JP Gleghorn, MMN Babadaei… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (NPs) have been used in numerous applications as anticancer, antibacterial
and antioxidant agents. Artificial engineering of protein interactions with NPs in biological …

Co-delivery of curcumin and paclitaxel by “core-shell” targeting amphiphilic copolymer to reverse resistance in the treatment of ovarian cancer

MD Zhao, JQ Li, FY Chen, W Dong… - International journal …, 2019 - Taylor & Francis
Background Ovarian cancer is a common malignancy in the female reproductive system with
a high mortality rate. The most important reason is multidrug resistance (MDR) of cancer …

New insights towards mesoporous silica nanoparticles as a technological platform for chemotherapeutic drugs delivery

RM Sabio, AB Meneguin, TC Ribeiro, RR Silva… - International Journal of …, 2019 - Elsevier
Mesoporous silica nanoparticles (MSNs) displays interesting properties for biomedical
applications such as high chemical stability, large surface area and tunable pores diameters …