[HTML][HTML] The role of epithelial-mesenchymal transition in regulating radioresistance

S Zhou, M Zhang, C Zhou, W Wang, H Yang… - Critical reviews in …, 2020 - Elsevier
Cancer patients with different stages can benefit from radiotherapy, but there are still limited
due to inherent or acquired radioresistance. The epithelial-mesenchymal transition (EMT) is …

Targeting epithelial-to-mesenchymal transition in radioresistance: crosslinked mechanisms and strategies

L Qiao, Y Chen, N Liang, J Xie, G Deng, F Chen… - Frontiers in …, 2022 - frontiersin.org
Radiotherapy exerts a crucial role in curing cancer, however, its treatment efficiency is
mostly limited due to the presence of radioresistance. Epithelial-to-mesenchymal transition …

A century of fractionated radiotherapy: how mathematical oncology can break the rules

N Ghaderi, J Jung, SC Brüningk… - International Journal of …, 2022 - mdpi.com
Radiotherapy is involved in 50% of all cancer treatments and 40% of cancer cures. Most of
these treatments are delivered in fractions of equal doses of radiation (Fractional Equivalent …

microRNAs: Potential glioblastoma radiosensitizer by targeting radiation-related molecular pathways

MT Bahreyni-Toossi, E Dolat, H Khanbabaei… - Mutation Research …, 2019 - Elsevier
Glioblastoma (GBM) is the most lethal type of primary brain tumor. Currently, even with
optimal and multimodal cancer therapies, the survival rate of GBM patients remains poor …

Myricetin loaded solid lipid nanoparticles upregulate MLKL and RIPK3 in human lung adenocarcinoma

L Khorsandi, E Mansouri, M Rashno… - International Journal of …, 2020 - Springer
Beneficial effects of MYC such as antioxidant, cytoprotective and antimicrobial activity have
been investigated in various studies. The aim of the present research was to evaluate the …

Dihydroartemisinin reduces irradiation-induced mitophagy and radioresistance in lung cancer A549 cells via CIRBP inhibition

S Wu, Z Li, H Li, K Liao - Life, 2022 - mdpi.com
Radiotherapy is a major therapeutic strategy for lung cancer, and radiation resistance
(radioresistance) is an important cause of residual and recurring cancer after treatment …

CB11, a novel purine-based PPARɣ ligand, overcomes radio-resistance by regulating ATM signalling and EMT in human non-small-cell lung cancer cells

TW Kim, DW Hong, JW Park, SH Hong - British Journal of Cancer, 2020 - nature.com
Background Peroxisome proliferator-activated receptor γ (PPARγ) agonists frequently
induce cell death in human non-small-cell lung cancer (NSCLC) cells. However, majority of …

Development of transient radioresistance during fractionated irradiation in vitro

J van den Berg, KCM Castricum, MH Meel… - Radiotherapy and …, 2020 - Elsevier
Background and purpose Effective combination treatments with fractionated radiotherapy
rely on a proper understanding of the dynamic responses that occur during treatment. We …

Local radiotherapy for murine breast cancer increases risk of metastasis by promoting the recruitment of M-MDSCs in lung

Z Zhang, Z Yao, Z Zhang, L Cui, L Zhang, G Qiu… - Cancer Cell …, 2023 - Springer
Background Radiotherapy is one of the effective methods for treatment of breast cancer;
however, controversies still exist with respect to radiotherapy for patients with TNBC. Here …

miR‐3059‐3p Regulates Glioblastoma Multiforme Radiosensitivity Enhancement through the Homologous Recombination Pathway of DNA Repair

YW Cheng, CJ Lin, SH Kuo, AS Lieu… - Journal of …, 2022 - Wiley Online Library
Background. Glioblastoma multiforme (GBM) is one of the most deadly and recalcitrant
illnesses of the neurocentral nervous system in humans. MicroRNAs (miRNAs) are a class of …