Oxidative stress response pathways in fungi

H Yaakoub, S Mina, A Calenda, JP Bouchara… - Cellular and Molecular …, 2022 - Springer
Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …

Comparative transcriptomics reveal possible mechanisms of amphotericin B resistance in Candida auris

R Shivarathri, S Jenull, M Chauhan… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Candida auris is an emerging multidrug-resistant human fungal pathogen often refractory to
treatment by all classes of antifungal drugs. Amphotericin B (AmB) is a fungicidal drug that …

Phosphoproteomic and Metabolomic Profiling Uncovers the Roles of CcPmk1 in the Pathogenicity of Cytospora chrysosperma

L Yu, Y Yang, D Xiong, C Tian - Microbiology spectrum, 2022 - Am Soc Microbiol
Pmk1, a highly conserved pathogenicity-related mitogen-activated protein kinase (MAPK) in
pathogenic fungi, is phosphorylated and activated by MAP2K and acts as a global regulator …

Host lung environment limits Aspergillus fumigatus germination through an SskA-dependent signaling response

ME Kirkland, MK Stannard, CH Kowalski, D Mould… - Msphere, 2021 - Am Soc Microbiol
Aspergillus fumigatus isolates display significant heterogeneity in growth, virulence,
pathology, and inflammatory potential in multiple murine models of invasive aspergillosis …

The Candida auris Hog1 MAP kinase is essential for the colonization of murine skin and intradermal persistence

R Shivarathri, M Chauhan, A Datta, D Das, A Karuli… - mBio, 2024 - journals.asm.org
Candida auris, a multidrug-resistant human fungal pathogen, was first identified in 2009 in
Japan. Since then, systemic C. auris infections have now been reported in more than 50 …

Interactions of the emerging fungus Candida auris with Acanthamoeba castellanii reveal phenotypic changes with direct implications on the response to stress and …

MR Valente, L Martins Alcântara, DS Cintra… - Microbiology …, 2024 - journals.asm.org
Candida auris is an emerging fungal pathogen notable for its resistance to multiple
antifungals and ability to survive in various environments. Understanding the interactions …

Genetic Transformation of Candida auris via Homology-Directed Repair Using a Standard Lithium Acetate Protocol

G Bravo Ruiz, A Lorenz - Candida auris: Methods and Protocols, 2022 - Springer
Reverse genetics is a particularly powerful tool in non-model organisms with known whole-
genome sequences enabling the characterization of gene and, thus, protein function via a …