[HTML][HTML] Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization

G Sanità, B Carrese, A Lamberti - Frontiers in molecular biosciences, 2020 - frontiersin.org
The use of nanoparticles (NP) in diagnosis and treatment of many human diseases,
including cancer, is of increasing interest. However, cytotoxic effects of NPs on cells and the …

Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects

SH Kiaie, N Majidi Zolbanin, A Ahmadi… - Journal of …, 2022 - Springer
In the last decade, the development of messenger RNA (mRNA) therapeutics by lipid
nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of …

Gelatin methacryloyl hydrogel, from standardization, performance, to biomedical application

J He, Y Sun, Q Gao, C He, K Yao… - Advanced …, 2023 - Wiley Online Library
Gelatin methacryloyl (GelMA), a photocurable hydrogel, is widely used in 3D culture,
particularly in 3D bioprinting, due to its high biocompatibility, tunable physicochemical …

Pharmacokinetics of magnetic iron oxide nanoparticles for medical applications

J Nowak-Jary, B Machnicka - Journal of Nanobiotechnology, 2022 - Springer
Magnetic iron oxide nanoparticles (MNPs) have been under intense investigation for at least
the last five decades as they show enormous potential for many biomedical applications …

Cannabinoid delivery systems for pain and inflammation treatment

N Bruni, C Della Pepa, S Oliaro-Bosso, E Pessione… - Molecules, 2018 - mdpi.com
There is a growing body of evidence to suggest that cannabinoids are beneficial for a range
of clinical conditions, including pain, inflammation, epilepsy, sleep disorders, the symptoms …

Combating implant infections: shifting focus from bacteria to host

S Amin Yavari, SM Castenmiller… - Advanced …, 2020 - Wiley Online Library
The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

J Liu, Z Liu, Y Pang, H Zhou - Journal of Nanobiotechnology, 2022 - Springer
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

Tumor-associated macrophages in osteosarcoma: from mechanisms to therapy

F Cersosimo, S Lonardi, G Bernardini, B Telfer… - International journal of …, 2020 - mdpi.com
Osteosarcomas (OSs) are bone tumors most commonly found in pediatric and adolescent
patients characterized by high risk of metastatic progression and recurrence after therapy …

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

VP Vu, GB Gifford, F Chen, H Benasutti, G Wang… - Nature …, 2019 - nature.com
Deposition of complement factors (opsonization) on nanoparticles may promote clearance
from the blood by macrophages and trigger proinflammatory responses, but the mechanisms …