Prior to the SARS-CoV-2 pandemic, antibiotic resistance was listed as the major global
health care priority. Some analyses, including the O'Neill report, have predicted that deaths …

Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …

Extracellular vesicles mediate community interactions among cells ranging from unicellular
microbes to complex vertebrates. Extracellular vesicles of the fungal pathogen Candida …

Candida albicans is a fungal pathogen that can form biofilms on medical devices and host
tissue, resulting in serious, life-threatening infections. These fungal biofilms are inherently …

The host type I interferon (IFN) pathway is a major signature of inflammation induced by the
human fungal pathogen, Candida albicans. However, the molecular mechanism for …

Exosomes are membrane extracellular vesicles secreted by almost all kinds of cells, which
are rich in proteins, lipids, and nucleic acids. As a medium of intercellular communication …

In this study, we investigated the influence of fungal extracellular vesicles (EVs) during
biofilm formation and morphogenesis in Candida albicans. Using crystal violet staining and …

The phyllosphere (ie, the aerial parts of plants) harbors a rich microbial life, including
bacteria, fungi, viruses, and yeasts. Current knowledge of yeasts stems primarily from …

Clinical infection due to Candida species frequently involve growth in biofilm communities.
Recalcitrance despite antifungal therapy leads to disease persistence associated with high …

Biofilms of the fungal pathogen Candida albicans include abundant long filaments called
hyphae. These cells express hypha-associated genes, which specify diverse virulence …