[HTML][HTML] Functions of gut microbiota metabolites, current status and future perspectives

J Liu, Y Tan, H Cheng, D Zhang, W Feng… - Aging and …, 2022 - ncbi.nlm.nih.gov
Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides
crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota …

Enhancement strategies for transdermal drug delivery systems: Current trends and applications

D Ramadon, MTC McCrudden, AJ Courtenay… - Drug delivery and …, 2021 - Springer
Transdermal drug delivery systems have become an intriguing research topic in
pharmaceutical technology area and one of the most frequently developed pharmaceutical …

RoboCap: Robotic mucus-clearing capsule for enhanced drug delivery in the gastrointestinal tract

SS Srinivasan, A Alshareef, AV Hwang, Z Kang… - Science robotics, 2022 - science.org
Oral drug delivery of proteins is limited by the degradative environment of the
gastrointestinal tract and poor absorption, requiring parenteral administration of these drugs …

Refinement of safety and efficacy of anti-cancer chemotherapeutics by tailoring their site-specific intracellular bioavailability through transporter modulation

P Dhakne, M Pillai, S Mishra, B Chatterjee… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Low intracellular bioavailability, off-site toxicities, and multi drug resistance (MDR) are the
major constraints involved in cancer chemotherapy. Many anticancer molecules fail to …

In Vitro and In Vivo Studies on HPMA-Based Polymeric Micelles Loaded with Curcumin

M Bagheri, MH Fens, TG Kleijn… - Molecular …, 2021 - ACS Publications
Curcumin-loaded polymeric micelles composed of poly (ethylene glycol)-b-poly (N-2-
benzoyloxypropyl methacrylamide)(mPEG-bp (HPMA-Bz)) were prepared to solubilize and …

Pharmacoeconomic analysis of the different therapeutic approaches in control of bovine mastitis: Phytotherapy and antimicrobial treatment

Z Kovačević, J Mihajlović, S Mugoša, O Horvat… - Antibiotics, 2022 - mdpi.com
Mastitis in dairy cows is responsible for major economic losses on dairy farms worldwide as
the most expensive and prevalent disease in dairy cattle. In spite of the fact that antibiotic …

Plant pharmacology: Insights into in-planta kinetic and dynamic processes of xenobiotics

T Malchi, S Eyal, H Czosnek, M Shenker… - Critical Reviews in …, 2022 - Taylor & Francis
The exposure of plants to pharmaceuticals via treated wastewater irrigation and biosolid
application presents an important route of chronic exposure of crops to a wide variety of …

Single-pill combination to improve hypertension treatment: pharmaceutical industry development

M Paczkowska-Walendowska, S Sip… - International Journal of …, 2022 - mdpi.com
Multiple illness is an increasingly common phenomenon. Its consequence is the need for
polytherapy, which is particularly common among people suffering from arterial …

Biotransformation of the azo dye reactive orange 16 by Aspergillus flavus A5P1: Performance, genetic background, pathway, and mechanism

W Qin, S Guo, Q Li, A Tang, H Liu, Y Liu - Journal of Hazardous Materials, 2024 - Elsevier
This study reports the strain Aspergillus flavus A5P1 (A5P1), which is with the capable of
degrading the azo dye reactive orange 16 (RO16). The mechanism of RO16 degradation by …

Evaluation of Antidiarrheal Activity of 80% Methanol Extract and Solvent Fractions of the Leaves of Withania somnifera (L.) Dunal in Swiss Albino Mice

G Tessema Desta, Y Andargie Ferede… - Evidence‐Based …, 2022 - Wiley Online Library
Background. Withaniasomnifera is an important medicinal plant for the treatment of diarrhea
in Ethiopian folklore medicine. The aim of this study was to evaluate the antidiarrheal activity …