Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity
K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …
claiming millions of lives and pushing healthcare systems in many countries to the brink …
Genetic polymorphisms of ACE1, ACE2, IFTM3, TMPRSS2 and TNFα genes associated with susceptibility and severity of SARS-CoV-2 infection: A systematic review …
V Pecoraro, M Cuccorese, T Trenti - Clinical and Experimental Medicine, 2023 - Springer
Background Some human polymorphisms of ACE1, ACE2, IFITM3, TMPRSS2 and TNFα
genes may have an effect on the susceptibility to SARS-CoV-2 infection and increase the …
genes may have an effect on the susceptibility to SARS-CoV-2 infection and increase the …
Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease
M Sabater Molina, E Nicolas Rocamora, AI Bendicho… - PloS one, 2022 - journals.plos.org
Background Infection by the SARS-Cov-2 virus produces in humans a disease of highly
variable and unpredictable severity. The presence of frequent genetic single nucleotide …
variable and unpredictable severity. The presence of frequent genetic single nucleotide …
[HTML][HTML] Potential genes associated with COVID-19 and comorbidity
S Feng, F Song, W Guo, J Tan, X Zhang… - … journal of medical …, 2022 - ncbi.nlm.nih.gov
Hypertension, diabetes mellitus, and coronary artery disease are common comorbidities and
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …
[HTML][HTML] The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity: A systematic review and meta-analysis
Genes involved in the regulation of viral recognition and its entry into a host cell have been
identified as candidates for genetic association studies on COVID-19 severity. Published …
identified as candidates for genetic association studies on COVID-19 severity. Published …
Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality
To elucidate the molecular mechanisms that manifest lung abnormalities during severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole …
Global distribution of ACE1 (rs4646994) and ACE2 (rs2285666) polymorphisms associated with COVID-19: A systematic review and meta-analysis
M Keikha, M Karbalaei - Microbial Pathogenesis, 2022 - Elsevier
Background Recent studies emphasize the significant impact of the renin-angiotensin
aldosterone system (RAAS) as a risk factor associated with severe acute respiratory …
aldosterone system (RAAS) as a risk factor associated with severe acute respiratory …
IFITM3, FURIN, ACE1, and TNF-α Genetic Association With COVID-19 Outcomes: Systematic Review and Meta-Analysis
JLF de Araújo, D Menezes, RS Aguiar… - Frontiers in …, 2022 - frontiersin.org
Human polymorphisms may contribute to SARS-CoV-2 infection susceptibility and COVID-
19 outcomes (asymptomatic presentation, severe COVID-19, death). We aimed to evaluate …
19 outcomes (asymptomatic presentation, severe COVID-19, death). We aimed to evaluate …
[HTML][HTML] Catch your breath: The protective role of the angiotensin AT2 receptor for the treatment of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease whereby
excessive deposition of extracellular matrix proteins (ECM) ultimately leads to respiratory …
excessive deposition of extracellular matrix proteins (ECM) ultimately leads to respiratory …
SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible
for COVID-19, has caused nearly 7 million deaths worldwide. Severe cases are marked by …
for COVID-19, has caused nearly 7 million deaths worldwide. Severe cases are marked by …