Highlights•Honey, as functional food, has health promoting and medicinal properties.•The
antioxidant property of honey plays a central role in its chemopreventive effect.•The …

Melanoma, one of the toughest tumors to treat, features high metastasis and high lethality.
Pinocembrin is a natural flavanone with versatile biological and pharmacological activities …

Colorectal cancer is becoming more common and deadly in both men and women
nowadays. Although various treatment interventions are available including chemotherapy …

The survival rate of breast cancer (BC) patients remains poor, thus the identification of safe
and effective new drugs is crucial to improve therapeutic outcomes and overall survival …

Manuka honey (MH) is a natural food with many beneficial properties to human health,
thanks to its high variety of bioactive compounds; however, little is known about its …

The exacerbation of progressive multiple sclerosis (MS) is closely associated with
obstruction of the differentiation of oligodendrocyte progenitor cells (OPCs). To discover …

Background: Colorectal cancer (CRC) is a common malignancy of digestive tract.
Pinocembrin (PINO) has been discovered to have a proapoptotic effect on CRC. This study …

Lappaconitine hydrochloride (LH), as a new synthetic alkaloid, exhibits antitumor activity,
whereas its antitumor effect on colorectal cancer (CRC) has not been investigated. In this …

Pharmaceutical companies are investigating more source matrices for natural bioactive
chemicals. Friedelin (friedelan-3-one) is a pentacyclic triterpene isolated from various plant …

Our phytochemical investigation of the roots of Uvaria siamensis led to the isolation of two
new lanostane triterpenes, 3-acetylpolycarpol (1) and 15-acetylpolycarpol (2), as well as 15 …