High-resolution single-cell atlas reveals diversity and plasticity of tissue-resident neutrophils in non-small cell lung cancer
Non-small cell lung cancer (NSCLC) is characterized by molecular heterogeneity with
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …
diverse immune cell infiltration patterns, which has been linked to therapy sensitivity and …
Mechanisms of hyperprogressive disease after immune checkpoint inhibitor therapy: what we (don't) know
S Camelliti, V Le Noci, F Bianchi, C Moscheni… - Journal of Experimental …, 2020 - Springer
Immune checkpoint inhibitors (ICIs) have made a breakthrough in the treatment of different
types of tumors, leading to improvement in survival, even in patients with advanced cancers …
types of tumors, leading to improvement in survival, even in patients with advanced cancers …
Crosstalk between the tumor microenvironment and cancer cells: a promising predictive biomarker for immune checkpoint inhibitors
X Li, Y Yang, Q Huang, Y Deng, F Guo… - Frontiers in Cell and …, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs) have changed the landscape of cancer treatment and
are emerging as promising curative treatments in different type of cancers. However, only a …
are emerging as promising curative treatments in different type of cancers. However, only a …
During early stages of cancer, neutrophils initiate anti-tumor immune responses in tumor-draining lymph nodes
E Pylaeva, G Korschunow, I Spyra, S Bordbari… - Cell Reports, 2022 - cell.com
Tumor-draining lymph nodes (LNs) play a crucial role during cancer spread and in initiation
of anti-cancer adaptive immunity. Neutrophils form a substantial population of cells in LNs …
of anti-cancer adaptive immunity. Neutrophils form a substantial population of cells in LNs …
[HTML][HTML] Prospective development and validation of a liquid immune profile-based signature (LIPS) to predict response of patients with recurrent/metastatic cancer to …
Background The predictive power of novel biological markers for treatment response to
immune checkpoint inhibitors (ICI) is still not satisfactory for the majority of patients with …
immune checkpoint inhibitors (ICI) is still not satisfactory for the majority of patients with …
Cemiplimab in an elderly frail population of patients with locally advanced or metastatic cutaneous squamous cell carcinoma: a single-center real-life experience from …
S Strippoli, A Fanizzi, D Quaresmini, A Nardone… - Frontiers in …, 2021 - frontiersin.org
Background Cutaneous squamous cell carcinoma (CSCC) is the second most common skin
cancer whose incidence is growing parallel to the lengthening of the average lifespan …
cancer whose incidence is growing parallel to the lengthening of the average lifespan …
Immunostimulatory properties of chemotherapy in breast cancer: From immunogenic modulation mechanisms to clinical practice
J Zhang, S Pan, C Jian, L Hao, J Dong, Q Sun… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) is the most common malignancy among females. Chemotherapy drugs
remain the cornerstone of treatment of BC and undergo significant shifts over the past 100 …
remain the cornerstone of treatment of BC and undergo significant shifts over the past 100 …
The immune endocannabinoid system of the tumor microenvironment
M Kienzl, J Kargl, R Schicho - International Journal of Molecular Sciences, 2020 - mdpi.com
Leukocytes are part of the tumor microenvironment (TME) and are critical determinants of
tumor progression. Because of the immunoregulatory properties of cannabinoids, the …
tumor progression. Because of the immunoregulatory properties of cannabinoids, the …
Neutrophils: Musketeers against immunotherapy
Neutrophils, the most copious leukocytes in human blood, play a critical role in
tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have …
tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have …
Basal and one-month differed neutrophil, lymphocyte and platelet values and their ratios strongly predict the efficacy of checkpoint inhibitors immunotherapy in …
M Guida, N Bartolomeo, D Quaresmini… - Journal of translational …, 2022 - Springer
Background To evaluate the capability of basal and one-month differed white blood cells
(WBC), neutrophil, lymphocyte and platelet values and their ratios (neutrophils-to …
(WBC), neutrophil, lymphocyte and platelet values and their ratios (neutrophils-to …