Optical imaging of live animals has grown into an important tool in biomedical research as
advances in photonic technology and reporter strategies have led to widespread exploration …

This is a review of recent mathematical and computational advances in optical tomography.
We discuss the physical foundations of forward models for light propagation on microscopic …

Bioluminescence tomography (BLT) is used to localize and quantify bioluminescent sources
in a small living animal. By advancing bioluminescent imaging to a tomographic framework …

For bioluminescence imaging studies in small animals, it is important to be able to
accurately localize the three-dimensional (3D) distribution of the underlying bioluminescent …

Many different types of radiation have been exploited to provide images of the structure and
function of tissues inside a living subject. Each imaging modality is characterized by differing …

A new method is described for obtaining a 3-D reconstruction of a bioluminescent light
source distribution inside a living animal subject, from multispectral images of the surface …

Abstract According to World Health Organization estimates, infectious organisms are
responsible for approximately one in four deaths worldwide. Animal models play an …

Bioluminescence tomography (BLT) is a new molecular imaging mode, which is being
actively developed to reveal molecular and cellular signatures as labeled by bioluminescent …

Diffuse optical tomography is emerging as a viable new biomedical imaging modality. Using
visible and near-infrared light this technique can probe the absorption and scattering …

As a new mode of molecular imaging, bioluminescence tomography (BLT) has become a
hot topic over the past two years. In this paper, a multilevel adaptive finite element algorithm …