[HTML][HTML] The emerging role of cell-free DNA as a molecular marker for cancer management

AJ Bronkhorst, V Ungerer, S Holdenrieder - Biomolecular detection and …, 2019 - Elsevier
An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

[HTML][HTML] Targets, pitfalls and reference materials for liquid biopsy tests in cancer diagnostics

E Geeurickx, A Hendrix - Molecular aspects of medicine, 2020 - Elsevier
Assessment of cell free DNA (cfDNA) and RNA (cfRNA), circulating tumor cells (CTC) and
extracellular vesicles (EV) in blood or other bodily fluids can enable early cancer detection …

Circulating cell-free nucleic acids and platelets as a liquid biopsy in the provision of personalized therapy for lung cancer patients

L Sorber, K Zwaenepoel, V Deschoolmeester… - Lung cancer, 2017 - Elsevier
Lung cancer is the predominant cause of cancer-related mortality in the world. The majority
of patients present with locally advanced or metastatic non-small-cell lung cancer (NSCLC) …

[HTML][HTML] Liquid biopsy: Cell-free DNA based analysis in breast cancer

K Venetis, G Cursano, C Pescia, M D'Ercole… - The Journal of Liquid …, 2023 - Elsevier
Breast cancer management has witnessed significant advancements, especially in the
diagnosis and treatment response monitoring through the implementation of imaging …

Mining nucleic acid “omics” to boost liquid biopsy in cancer

A Tivey, RJ Lee, A Clipson, SM Hill, P Lorigan… - Cell Reports …, 2024 - cell.com
Treatments for cancer patients are becoming increasingly complex, and there is a growing
desire from clinicians and patients for biomarkers that can account for this complexity to …

Cell-free DNA: an overview of sample types and isolation procedures

F Martignano - Cell-free DNA as Diagnostic Markers: Methods and …, 2019 - Springer
The study of cell-free DNA (cfDNA) is often challenging due to genomic DNA contamination,
low concentration, and high fragmentation. Therefore, it is important to optimize pre …

Comparison of cell-free and small extracellular-vesicle-associated DNA by sequencing plasma of lung cancer patients

N Moldovan, S Verkuijlen, Y van der Pol, L Bosch… - Iscience, 2024 - cell.com
Blood contains multiple analytes that can be used as liquid biopsy to analyze cancer.
Mutations have been detected in DNA associated with small extracellular vesicles (sEVs) …

Cell-free DNA in the liquid biopsy context: role and differences between ctDNA and CTC marker in cancer management

P Fici - Cell-free DNA as Diagnostic Markers: Methods and …, 2019 - Springer
Liquid biopsy is a new diagnostic concept to investigate the molecular features of solid
tumors by blood, saliva, urine, and any other body fluids which show a source of potential …

Combining the amplification refractory mutation system and high-resolution melting analysis for KRAS mutation detection in clinical samples

BB Oliveira, B Costa, B Morão, S Faias… - Analytical and …, 2023 - Springer
The success of personalized medicine depends on the discovery of biomarkers that allow
oncologists to identify patients that will benefit from a particular targeted drug. Molecular …

[HTML][HTML] Identification of liquid biopsy-based mutations in colorectal cancer by targeted sequencing assays

I Szász, T Kiss, A Mokánszki, V Koroknai, J Deák… - Molecular and Cellular …, 2023 - Elsevier
Recently, liquid biopsy, as a promising approach was introduced for the analysis of different
tumor-derived circulating markers including tumor DNA and cell free DNA (ct/cfDNA) …